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Synthetic organometallic chemistry directed towards new ligands, complexes,
materials, and catalysts
We are interested in the chemistry of functionalized phosphines derived
from ferrocene, focusing mainly on ferrocene
phosphinocarboxylic acids. Compounds of this type, which combine various
donor groups, are versatile and highly variable ligands, capable of
coordinating to almost any transition metal and in diverse coordination
modes including hemilabile ones.
The history
of ferrocenecarboxylic acid started in 1996, when we reported about the
first compound of this class, Hdpf (see Figure below). Since then
we have synthesized a range of the related compounds and studied their coordination and structural chemistry. More recently, we turned
also to applications of the ligands and complexes in catalysis of organic
reactions (e.g., Heck and Suzuki coupling reactions, Pd-catalyzed allylic
substitution), and further synthetic utility of the phosphinocarboxylic
ligands in organometallic synthesis.
This
led us also to further extensions of ferrocene chemistry towards, e.g.,
to organometallic chemistry of ferrocene alkynes (as ligands and
synthons), and applications of ferrocene compounds in the preparation of
self-assembled crystalline materials and ferrocene labelled biomolecules.
To
characterize new compounds synthesized in our group, we combine the
standard solid-state measurements (X-ray diffraction) and spectral
methods (NMR, IR, UV-vis and MS) with special techniques such as
electrochemical measurements and 57Fe Moessbauer spectroscopy
to help understanding of variations to the structures studied for further
ligand development. More information about our research interests can be
obtained from the listing of publications.
We
have collaborative research projects with the groups of:
Dr. Karel
Mach (organometallic synthesis)
Professor Jiří Čejka
(catalysis) and
Dr. Jiří
Ludvík (electrochemistry) all from the J. Heyrovský Institute
of Physical Chemistry, Academy of Sciences of the Czech Republic
Professor Anna M.
Trzeciak and Professor Józef J. Ziolkowski at the Faculty of
Chemistry, University of Wroclaw, Poland (catalysis)
Professor Martin Kotora at
the Department of Organic chemistry, Faculty of Science, Charles
University (organic ferrocene derivatives)
Professor Dalimil
Dvořák from the Institute of Organic Chemistry, Institute of Chemical
Technology, Prague (organometallic chemistry)
Dr. Martin Hocek at Institute of
Organic Chemistry and Biochemistry, Academy of Sciences of
the Czech Republic (ferrocene-labelled purines)
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