{"id":5430,"date":"2022-02-01T10:42:53","date_gmt":"2022-02-01T10:42:53","guid":{"rendered":"https:\/\/web.natur.cuni.cz\/testwp\/?page_id=5430"},"modified":"2024-12-26T04:06:54","modified_gmt":"2024-12-26T04:06:54","slug":"cv-ondrej-vanek","status":"publish","type":"page","link":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/cv-ondrej-vanek\/","title":{"rendered":"Curriculum Vitae &#8211; RNDr. Ond\u0159ej Van\u011bk, Ph.D."},"content":{"rendered":"\n<p class=\"has-text-align-center\"><em>Head of the Laboratory of Structural Biochemistry of Immune Recognition at Charles University, Prague, Czech Republic<\/em><\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image is-resized\">\n<figure class=\"alignleft size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1011\" src=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/Obrazek-1-small-1-1024x1011.jpg\" alt=\"\" class=\"wp-image-6538\" style=\"width:387px;height:auto\" srcset=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/Obrazek-1-small-1-1024x1011.jpg 1024w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/Obrazek-1-small-1-300x296.jpg 300w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/Obrazek-1-small-1-768x758.jpg 768w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/Obrazek-1-small-1-1536x1517.jpg 1536w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/Obrazek-1-small-1-2048x2022.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<div class=\"wp-block-columns alignwide are-vertically-aligned-top is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<h5 class=\"wp-block-heading\" id=\"research-profiles\" style=\"font-style:normal;font-weight:700\">Research profiles<\/h5>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list uagb-block-4cd9c65a uagb-icon-list__outer-wrap uagb-icon-list__layout-horizontal\"><div class=\"uagb-icon-list__wrap\">\n<div class=\"wp-block-uagb-icon-list-child uagb-block-474dfd0d\"><a target=\"_blank\" aria-label=\"ResearchGate \" rel=\"noopener noreferrer\" href=\"https:\/\/www.researchgate.net\/profile\/Ondrej-Vanek-2\"> <\/a><span class=\"uagb-icon-list__source-wrap\"><img decoding=\"async\" class=\"uagb-icon-list__source-image\" src=\"http:\/\/web.natur.cuni.cz\/gis\/eo4landscape\/wp-content\/uploads\/2021\/01\/researchgate_icon_130843-2.png\" width=\"25\" height=\"25\" loading=\"lazy\" alt=\"\"\/><\/span><span class=\"uagb-icon-list__label\">ResearchGate <\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list-child uagb-block-93502044\"><a target=\"_blank\" aria-label=\"Google Scholar\" rel=\"noopener noreferrer\" href=\"https:\/\/scholar.google.com\/citations?hl=cs&amp;user=WOU91ZsAAAAJ\"> <\/a><span class=\"uagb-icon-list__source-wrap\"><img decoding=\"async\" class=\"uagb-icon-list__source-image\" src=\"http:\/\/web.natur.cuni.cz\/gis\/eo4landscape\/wp-content\/uploads\/2021\/01\/scholar-2.png\" width=\"25\" height=\"25\" loading=\"lazy\" alt=\"\"\/><\/span><span class=\"uagb-icon-list__label\">Google Scholar<\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list-child uagb-block-627adc2a uagb-icon-list-repeater uagb-icon-list__wrapper\"><a target=\"_blank\" aria-label=\"ORCID ID\" rel=\"noopener noreferrer\" href=\"https:\/\/orcid.org\/0000-0003-1190-8535\"> <\/a><span class=\"uagb-icon-list__source-wrap\"><img decoding=\"async\" class=\"uagb-icon-list__source-image\" src=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2021\/01\/1200px-ORCID_iD.svg_-2.png\" width=\"25\" height=\"25\" loading=\"lazy\" alt=\"orcid icon\"\/><\/span><span class=\"uagb-icon-list__label\">ORCID ID<\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list-child uagb-block-1840ebca\"><a target=\"_blank\" aria-label=\"LinkedIN\" rel=\"noopener noreferrer\" href=\"https:\/\/www.linkedin.com\/in\/ond%C5%99ej-van%C4%9Bk-372bb673\/\"> <\/a><span class=\"uagb-icon-list__source-wrap\"><img decoding=\"async\" class=\"uagb-icon-list__source-image\" src=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2021\/01\/linkedin-2.png\" width=\"25\" height=\"25\" loading=\"lazy\" alt=\"\"\/><\/span><span class=\"uagb-icon-list__label\">LinkedIN<\/span><\/div>\n<\/div><\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list uagb-block-3a3c07b5 uagb-icon-list__outer-wrap uagb-icon-list__layout-horizontal\"><div class=\"uagb-icon-list__wrap\">\n<div class=\"wp-block-uagb-icon-list-child uagb-block-5e06bbab uagb-icon-list-repeater uagb-icon-list__wrapper\"><a target=\"_blank\" aria-label=\"e-mail: ondrej.vanek@natur.cuni.cz\" rel=\"noopener noreferrer\" href=\"mailto: ondrej.vanek@natur.cuni.cz\"> <\/a><span class=\"uagb-icon-list__source-wrap\"><img decoding=\"async\" class=\"uagb-icon-list__source-image\" src=\"http:\/\/web.natur.cuni.cz\/gis\/eo4landscape\/wp-content\/uploads\/2021\/01\/email-3.png\" width=\"25\" height=\"25\" loading=\"lazy\" alt=\"\"\/><\/span><span class=\"uagb-icon-list__label\">e-mail: <a href=\"mailto:daniel.paluba@natur.cuni.cz\">ondrej.vanek@natur.cuni.cz<\/a><\/span><\/div>\n<\/div><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">Research interests<\/h5>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Deciphering the mystery of life by understanding how life works on a molecular basis <\/li>\n\n\n\n<li>Rational design of therapeutic proteins and novel immunotherapeutics <\/li>\n\n\n\n<li>Living molecules: structural biology of the cell, structural immunology <\/li>\n\n\n\n<li>Transfer of knowledge and technology to real life and practical use<\/li>\n<\/ul>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">Vision for our research group<\/h5>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>We are a well-functioning research team pursuing exciting projects bringing health and prosperity!<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-7c7ccc74\"><h3 class=\"uagb-heading-text\"><strong>Education<\/strong><\/h3><div class=\"uagb-separator\"><\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-content-timeline uagb-timeline__outer-wrap uagb-block-28265c72-f054-4ddc-a92a-5327c2a1477e uagb-timeline__content-wrap uagb-timeline__center-block  uagb-timeline__arrow-center uagb-timeline\">\n<article class=\"wp-block-uagb-content-timeline-child uagb-timeline__field uagb-timeline-child-18e67aff-0c3c-414a-944d-713e890fdf6b uagb-timeline__right uagb-timeline__field-wrap\"><div class=\"uagb-timeline__marker out-view-uagb-timeline__icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M160 32V64H288V32C288 14.33 302.3 0 320 0C337.7 0 352 14.33 352 32V64H400C426.5 64 448 85.49 448 112V160H0V112C0 85.49 21.49 64 48 64H96V32C96 14.33 110.3 0 128 0C145.7 0 160 14.33 160 32zM0 192H448V464C448 490.5 426.5 512 400 512H48C21.49 512 0 490.5 0 464V192zM64 304C64 312.8 71.16 320 80 320H112C120.8 320 128 312.8 128 304V272C128 263.2 120.8 256 112 256H80C71.16 256 64 263.2 64 272V304zM192 304C192 312.8 199.2 320 208 320H240C248.8 320 256 312.8 256 304V272C256 263.2 248.8 256 240 256H208C199.2 256 192 263.2 192 272V304zM336 256C327.2 256 320 263.2 320 272V304C320 312.8 327.2 320 336 320H368C376.8 320 384 312.8 384 304V272C384 263.2 376.8 256 368 256H336zM64 432C64 440.8 71.16 448 80 448H112C120.8 448 128 440.8 128 432V400C128 391.2 120.8 384 112 384H80C71.16 384 64 391.2 64 400V432zM208 384C199.2 384 192 391.2 192 400V432C192 440.8 199.2 448 208 448H240C248.8 448 256 440.8 256 432V400C256 391.2 248.8 384 240 384H208zM320 432C320 440.8 327.2 448 336 448H368C376.8 448 384 440.8 384 432V400C384 391.2 376.8 384 368 384H336C327.2 384 320 391.2 320 400V432z\"><\/path><\/svg><\/div><div class=\"uagb-timeline__day-new uagb-timeline__day-right uagb-timeline__events-inner-new\"><div class=\"uagb-timeline__events-inner--content\"><div class=\"uagb-timeline__date-hide uagb-timeline__inner-date-new\">2019<\/div><h4 class=\"uagb-timeline__heading\">Research internship<\/h4><p class=\"uagb-timeline-desc-content\"><strong>05-08\/2019<\/strong><br>Biophysics group, Institute of Applied Physics, Technical University of Vienna<\/p><div class=\"uagb-timeline__arrow\"><\/div><\/div><\/div><div class=\"uagb-timeline__date-new\">2019<\/div><\/article>\n\n\n\n<article class=\"wp-block-uagb-content-timeline-child uagb-timeline__field uagb-timeline-child-08eb9582-9a12-4010-bf37-1bf15641fa62 uagb-timeline__left uagb-timeline__field-wrap\"><div class=\"uagb-timeline__marker out-view-uagb-timeline__icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M160 32V64H288V32C288 14.33 302.3 0 320 0C337.7 0 352 14.33 352 32V64H400C426.5 64 448 85.49 448 112V160H0V112C0 85.49 21.49 64 48 64H96V32C96 14.33 110.3 0 128 0C145.7 0 160 14.33 160 32zM0 192H448V464C448 490.5 426.5 512 400 512H48C21.49 512 0 490.5 0 464V192zM64 304C64 312.8 71.16 320 80 320H112C120.8 320 128 312.8 128 304V272C128 263.2 120.8 256 112 256H80C71.16 256 64 263.2 64 272V304zM192 304C192 312.8 199.2 320 208 320H240C248.8 320 256 312.8 256 304V272C256 263.2 248.8 256 240 256H208C199.2 256 192 263.2 192 272V304zM336 256C327.2 256 320 263.2 320 272V304C320 312.8 327.2 320 336 320H368C376.8 320 384 312.8 384 304V272C384 263.2 376.8 256 368 256H336zM64 432C64 440.8 71.16 448 80 448H112C120.8 448 128 440.8 128 432V400C128 391.2 120.8 384 112 384H80C71.16 384 64 391.2 64 400V432zM208 384C199.2 384 192 391.2 192 400V432C192 440.8 199.2 448 208 448H240C248.8 448 256 440.8 256 432V400C256 391.2 248.8 384 240 384H208zM320 432C320 440.8 327.2 448 336 448H368C376.8 448 384 440.8 384 432V400C384 391.2 376.8 384 368 384H336C327.2 384 320 391.2 320 400V432z\"><\/path><\/svg><\/div><div class=\"uagb-timeline__day-new uagb-timeline__day-left uagb-timeline__events-inner-new\"><div class=\"uagb-timeline__events-inner--content\"><div class=\"uagb-timeline__date-hide uagb-timeline__inner-date-new\">2018<\/div><h4 class=\"uagb-timeline__heading\">Research internship<\/h4><p class=\"uagb-timeline-desc-content\">06-09\/2018<br>Protein Technologies Facility, Biocenter, University of Vienna<\/p><div class=\"uagb-timeline__arrow\"><\/div><\/div><\/div><div class=\"uagb-timeline__date-new\">2018<\/div><\/article>\n\n\n\n<article class=\"wp-block-uagb-content-timeline-child uagb-timeline__field uagb-timeline-child-c554661c-7eb3-4f7b-beba-e0fe670fa658 uagb-timeline__right uagb-timeline__field-wrap\"><div class=\"uagb-timeline__marker out-view-uagb-timeline__icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M160 32V64H288V32C288 14.33 302.3 0 320 0C337.7 0 352 14.33 352 32V64H400C426.5 64 448 85.49 448 112V160H0V112C0 85.49 21.49 64 48 64H96V32C96 14.33 110.3 0 128 0C145.7 0 160 14.33 160 32zM0 192H448V464C448 490.5 426.5 512 400 512H48C21.49 512 0 490.5 0 464V192zM64 304C64 312.8 71.16 320 80 320H112C120.8 320 128 312.8 128 304V272C128 263.2 120.8 256 112 256H80C71.16 256 64 263.2 64 272V304zM192 304C192 312.8 199.2 320 208 320H240C248.8 320 256 312.8 256 304V272C256 263.2 248.8 256 240 256H208C199.2 256 192 263.2 192 272V304zM336 256C327.2 256 320 263.2 320 272V304C320 312.8 327.2 320 336 320H368C376.8 320 384 312.8 384 304V272C384 263.2 376.8 256 368 256H336zM64 432C64 440.8 71.16 448 80 448H112C120.8 448 128 440.8 128 432V400C128 391.2 120.8 384 112 384H80C71.16 384 64 391.2 64 400V432zM208 384C199.2 384 192 391.2 192 400V432C192 440.8 199.2 448 208 448H240C248.8 448 256 440.8 256 432V400C256 391.2 248.8 384 240 384H208zM320 432C320 440.8 327.2 448 336 448H368C376.8 448 384 440.8 384 432V400C384 391.2 376.8 384 368 384H336C327.2 384 320 391.2 320 400V432z\"><\/path><\/svg><\/div><div class=\"uagb-timeline__day-new uagb-timeline__day-right uagb-timeline__events-inner-new\"><div class=\"uagb-timeline__events-inner--content\"><div class=\"uagb-timeline__date-hide uagb-timeline__inner-date-new\">2005 &#8211; 2010<\/div><h4 class=\"uagb-timeline__heading\">Doctoral programme<\/h4><p class=\"uagb-timeline-desc-content\"><strong>Biochemistry<\/strong><br><br>Dept. of Biochemistry, Faculty of Science, Charles University<\/p><div class=\"uagb-timeline__arrow\"><\/div><\/div><\/div><div class=\"uagb-timeline__date-new\">2005 &#8211; 2010<\/div><\/article>\n\n\n\n<article class=\"wp-block-uagb-content-timeline-child uagb-timeline__field uagb-timeline-child-1961b82c-c8bc-450e-b5b4-8e3f916794a5 uagb-timeline__left uagb-timeline__field-wrap\"><div class=\"uagb-timeline__marker out-view-uagb-timeline__icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M160 32V64H288V32C288 14.33 302.3 0 320 0C337.7 0 352 14.33 352 32V64H400C426.5 64 448 85.49 448 112V160H0V112C0 85.49 21.49 64 48 64H96V32C96 14.33 110.3 0 128 0C145.7 0 160 14.33 160 32zM0 192H448V464C448 490.5 426.5 512 400 512H48C21.49 512 0 490.5 0 464V192zM64 304C64 312.8 71.16 320 80 320H112C120.8 320 128 312.8 128 304V272C128 263.2 120.8 256 112 256H80C71.16 256 64 263.2 64 272V304zM192 304C192 312.8 199.2 320 208 320H240C248.8 320 256 312.8 256 304V272C256 263.2 248.8 256 240 256H208C199.2 256 192 263.2 192 272V304zM336 256C327.2 256 320 263.2 320 272V304C320 312.8 327.2 320 336 320H368C376.8 320 384 312.8 384 304V272C384 263.2 376.8 256 368 256H336zM64 432C64 440.8 71.16 448 80 448H112C120.8 448 128 440.8 128 432V400C128 391.2 120.8 384 112 384H80C71.16 384 64 391.2 64 400V432zM208 384C199.2 384 192 391.2 192 400V432C192 440.8 199.2 448 208 448H240C248.8 448 256 440.8 256 432V400C256 391.2 248.8 384 240 384H208zM320 432C320 440.8 327.2 448 336 448H368C376.8 448 384 440.8 384 432V400C384 391.2 376.8 384 368 384H336C327.2 384 320 391.2 320 400V432z\"><\/path><\/svg><\/div><div class=\"uagb-timeline__day-new uagb-timeline__day-left uagb-timeline__events-inner-new\"><div class=\"uagb-timeline__events-inner--content\"><div class=\"uagb-timeline__date-hide uagb-timeline__inner-date-new\">2000 \u2013 2005<\/div><h4 class=\"uagb-timeline__heading\">Master programme<\/h4><p class=\"uagb-timeline-desc-content\"><strong>Biochemistry<\/strong><br><br>Dept. of Biochemistry, Faculty of Science, Charles University<\/p><div class=\"uagb-timeline__arrow\"><\/div><\/div><\/div><div class=\"uagb-timeline__date-new\">2000 \u2013 2005<\/div><\/article>\n<div class=\"uagb-timeline__line\"><div class=\"uagb-timeline__line__inner\"><\/div><\/div><\/div>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-dd0acfbc\"><h3 class=\"uagb-heading-text\"><strong>Selected special courses and workshops<\/strong><\/h3><div class=\"uagb-separator\"><\/div><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><tbody><tr><td><strong>2020<\/strong><\/td><td><a href=\"https:\/\/arbre-mobieu.eu\/prague-2020-home\/\"><strong>ARBRE-MOBIEU 2020 Plenary Meeting<\/strong><\/a><strong>, <\/strong>Prague 24.-26. 2. 2020<strong> (main organizer)<\/strong><\/td><\/tr><tr><td><strong>2018<\/strong><\/td><td><strong>FEBS Instruct MOBIEU Practical Course <\/strong><a href=\"https:\/\/biomacromoldynamics2018.febsevents.org\/\"><strong>Hydrodynamic and thermodynamic analysis of biological macromolecules and their interactions<\/strong><\/a> <strong>(main organizer; <\/strong><a href=\"https:\/\/biomacromoldynamics2020.febsevents.org\/\"><strong>2020 &#8211; organizer<\/strong><\/a><strong>)<\/strong><\/td><\/tr><tr><td><strong>2017<\/strong><\/td><td><a href=\"https:\/\/www.xray.cz\/pa\/\"><strong>Proteins in Action<\/strong><\/a><strong> (speaker) <\/strong>and <a href=\"https:\/\/p4eu.org\/prague-2017\"><strong>Proteins for Life<\/strong><\/a><strong> (main organizer) <\/strong>international conferences<\/td><\/tr><tr><td><strong>2016<\/strong><\/td><td>Workshop for the hydrodynamic and thermodynamic analysis of biological macromolecules and their interactions with SEDFIT and SEDPHAT<\/td><\/tr><tr><td><strong>2016<\/strong><\/td><td><strong>FEBS Advanced Course <\/strong><a href=\"http:\/\/nh.cas.cz\/febslbtp2016\/\"><strong>Ligand Binding Theory and Practice<\/strong><\/a><strong> (speaker; <\/strong><a href=\"https:\/\/ligandbinding2018.febsevents.org\/\"><strong>2018 \u2013 tutor<\/strong><\/a><strong>)<\/strong><\/td><\/tr><tr><td><strong>2012<\/strong><\/td><td>EU-KTS Trans-national technology transfer manager junior \/ senior certified courses<\/td><\/tr><tr><td><strong>2011<\/strong><\/td><td>P-CUBE workshop on Advances in Protein Crystallization<\/td><\/tr><tr><td><strong>2009<\/strong><\/td><td><strong>SPINE2 Discussion workshop on Eukaryotic expression (main organizer)<\/strong>, SPINE2 course New strategies for cloning &amp; expression of protein complexes in <em>E. coli<\/em> and insect cells<\/td><\/tr><tr><td><strong>2008<\/strong><\/td><td>SPINE2 Biophysical Characterization of Macromolecular Complexes workshop, EMBO Practical Course on the Structural Characterization of Macromolecular Complexes<\/td><\/tr><tr><td><strong>2007<\/strong><\/td><td>TeachSG workshop on Biological macromolecules and their ligands, techniques in X-ray structure analysis and docking, HSC6 &#8211; Hercules Specialized Course on Advances and New Applications of Synchrotron Radiation for Structural Biology, SPINE2 Discussion workshop on protein co-expression<\/td><\/tr><tr><td><strong>2004<\/strong><\/td><td>FEBS Advanced course &#8211; Advanced methods in protein crystallization<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-4595de4d\"><h3 class=\"uagb-heading-text\"><strong>Awards<\/strong><\/h3><div class=\"uagb-separator\"><\/div><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><tbody><tr><td><strong>2017<\/strong><\/td><td>Award for the best poster at the AUC2017 international conference from the British Biophysical Society<\/td><\/tr><tr><td><strong>2014<\/strong><\/td><td>Instruct Research &amp; Development Pilot Project Award (structural biology of NK cell receptors)<\/td><\/tr><tr><td><strong>2014<\/strong><\/td><td>Award &#8220;Velemlok&#8221; for the best teachers in the last academic year based on the student questionnaire<\/td><\/tr><tr><td><strong>2010<\/strong><\/td><td>PhD. in Biochemistry at the Faculty of Science, Charles University, doctoral thesis &#8220;Structure and function of C-type lectin NK cell receptors studied by recombinant expression and protein crystallography&#8221;<\/td><\/tr><tr><td><strong>2006<\/strong><\/td><td>Award for the best diploma thesis in 2005 from the director of the Institute of Microbiology of the Czech Academy of Sciences; Award for the best oral presentation given in &#8220;Young Section&#8221; of the 10<sup>th<\/sup> Work Meeting of Biochemists and Molecular Biologists, selected participant of FEBS Young Scientist Forum for Czech Republic at 31<sup>st<\/sup> FEBS Congress<\/td><\/tr><tr><td><strong>2005<\/strong><\/td><td>Graduated from the Faculty of Science of the Charles University, diploma thesis &#8220;Preparation and structural studies of protein CD69, receptor of human natural killer cells&#8221;<\/td><\/tr><tr><td><strong>2000<\/strong><\/td><td>Bronze medal at the 32<sup>nd<\/sup> International Chemistry Olympiad; Award from The Learned Society of the Czech Republic; Award from The Ministry of Education, Youth and Sport for international representation<\/td><\/tr><tr><td><\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-64eb5fe3\"><h3 class=\"uagb-heading-text\"><strong>Activities and positions<\/strong><\/h3><div class=\"uagb-separator\"><\/div><p class=\"uagb-desc-text\">Author or co-author of <strong>186<\/strong> contributions at scientific meetings, <strong>1<\/strong> patent, and <strong>51 publications<\/strong> in peer-reviewed journals (WoS), <strong>1278 times cited<\/strong> (1166 times without self-citations; WoS), <strong>H-index 19<\/strong>. Responsible for <strong>20<\/strong> research grants and <strong>1<\/strong> award, involved in several international projects, organizer of <strong>2<\/strong> international training workshops and <strong>2<\/strong> international conferences, <strong>supervisor<\/strong> of <strong>45<\/strong> bachelor&#8217;s, <strong>32<\/strong> master&#8217;s, and <strong>5<\/strong> doctoral theses (4\/5\/2 ongoing), <strong>head <\/strong>of <strong>2<\/strong> practical courses, and <strong>teacher<\/strong> of <strong>3<\/strong> subjects in bachelor and master study programs in biochemistry.<\/p><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><tbody><tr><td><strong>2022-present<\/strong><\/td><td>COST Action CA21135 &#8220;<a href=\"https:\/\/www.immuno-model.eu\/\">IMMUNO-model<\/a>&#8221; member<\/td><\/tr><tr><td><strong>2019-2023<\/strong><\/td><td>COST Action CA18103 &#8220;<a href=\"https:\/\/innogly.eu\/\">INNOGLY<\/a>&#8221; Management Committee member and member of the Communication, Training schools, and STSM committees<\/td><\/tr><tr><td><strong>2016-2020<\/strong><\/td><td>&nbsp;COST Action CA15126 &#8220;<a href=\"http:\/\/arbre-mobieu.eu\/\">MOBIEU<\/a>&#8221; Management Committee member and STSM coordinator<\/td><\/tr><tr><td><strong>2016-present<\/strong><\/td><td>Reviewer of grant proposals submitted to the INTER-EXCELLENCE I &amp; II programs of the MEYS CR<\/td><\/tr><tr><td><strong>2015-present<\/strong><\/td><td>Head of the <a href=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/\">Laboratory of Structural Biochemistry of Immune Recognition<\/a> research group at the Department of Biochemistry, Faculty of Science, Charles University<\/td><\/tr><tr><td><strong>2014-2015<\/strong><\/td><td>Mentee program of the director of the <a href=\"https:\/\/www.biocev.eu\/\">BIOCEV<\/a> institute<\/td><\/tr><tr><td><strong>2012-2022<\/strong><\/td><td>Technological scout at the Charles University Centre for Knowledge and Technology Transfer (part-time)<\/td><\/tr><tr><td><strong>2011-present<\/strong><\/td><td>Member of Protein Production and Purification Partnership in Europe initiative (<a href=\"https:\/\/p4eu.org\/\">P4EU<\/a>)<\/td><\/tr><tr><td><strong>2011<\/strong><\/td><td>Implementation of recombinant protein expression in HEK293 cells at the Department of Biochemistry<\/td><\/tr><tr><td><strong>2011-present<\/strong><\/td><td>Research Assistant at the Department of Biochemistry, Faculty of Science, Charles University (full-time)<\/td><\/tr><tr><td><strong>2007<\/strong><\/td><td>Implementation of analytical ultracentrifugation at the Department of Biochemistry<\/td><\/tr><tr><td><strong>2006-present<\/strong><\/td><td>Member of Czech Society for Biochemistry and Molecular Biology (FEBS constituent society)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-ae9c5f06\"><h3 class=\"uagb-heading-text\"><strong>Awarded research projects<\/strong><\/h3><div class=\"uagb-separator\"><\/div><\/div>\n\n\n\n<ol style=\"list-style-type:1\" class=\"wp-block-list\">\n<li>Exploiting molecular mechanisms of natural killer cell recognition for antitumor therapy. MEYS CR (LUAUS25250), 2025-2028, <strong>principal investigator<\/strong><\/li>\n\n\n\n<li>Structural immunology of NK cell recognition: from tumor evasion to its eradication. Czech Science Foundation (25-18490S), 2025-2027,<strong> principal investigator<\/strong><\/li>\n\n\n\n<li>Nanoscale organization of NK cell receptor-ligand complexes through the optics of quantitative single-molecule microscopy. Czech Science Foundation (23-08490L; trilateral international project), 2023-2026,<strong> principal investigator<\/strong><\/li>\n\n\n\n<li>Glycan-dependent regulation of NK cell recognition: structural biology and novel methods of glycopeptide analysis. MEYS CR (LTC20078; in the frame of the COST Action CA18103 <a href=\"https:\/\/innogly.eu\/\">INNOGLY: Innovation with Glycans<\/a>), 2020-2023, <strong>principal investigator<\/strong><\/li>\n\n\n\n<li>Novel clinically relevant IL-2 immunotherapeutics for cancer treatment. Czech Science Foundation (20-13029S), 2020-2022,<strong> co-investigator<\/strong><\/li>\n\n\n\n<li>New ligands for old receptors of human natural killer cells: structure, assembly within the immune synapse and potential for therapy. Czech Science Foundation (18-10687S), 2018-2021, <strong>principal investigator<\/strong><\/li>\n\n\n\n<li>Utilization of integrative molecular biophysical approaches for the functional studies of human natural killer cell receptors and formation of their complexes with tumour ligands. MEYS CR (LTC17065; in the frame of the COST Action CA15126 <a href=\"http:\/\/arbre-mobieu.eu\/\">MOBIEU: Molecular Biophysics in Europe<\/a>), 2017-2020, <strong>principal investigator<\/strong><\/li>\n\n\n\n<li>During 2016-2023, supervised MSc. and PhD. students were awarded 10 projects from the Charles University Grant Agency (161216, 927916, 1740318, 1378219, 1436020, 1436220, 318122, 358322, 173923, 285423), <strong>project leader<\/strong><\/li>\n\n\n\n<li>Harnessing soluble forms of NK cell receptors and their ligands for the generation of novel anticancer immunotherapeutics. Czech Science Foundation (15-15181S), 2015-2017, <strong>principal investigator<\/strong><\/li>\n\n\n\n<li>Participation in EU-funded structural biology projects P-CUBE, BioStruct-X, Instruct, and iNEXT, 2011-2017, more than 10 accesses to various facilities abroad were granted to students of mine, including one two-month-long Instruct internship and two <a href=\"https:\/\/instruct-eric.eu\/rd-pilot-project-awards\">Instruct R&amp;D Pilot Project awards<\/a>, <strong>principal investigator<\/strong> at all applications<\/li>\n\n\n\n<li>SPINE2:Complexes. Integrated project EC 6FP No. LSH-2005-031220, coordinator prof. D. Stuart, Oxford University, 2006-2010, <strong>member of the research team<\/strong> at the Institute of Microbiology, AS CR<\/li>\n<\/ol>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-e29a7cd6\"><h3 class=\"uagb-heading-text\"><strong>The 10 most significant publications<\/strong><\/h3><div class=\"uagb-separator\"><\/div><p class=\"uagb-desc-text\">The complete list at <a href=\"http:\/\/orcid.org\/0000-0003-1190-8535\">ORCID<\/a>, <a href=\"https:\/\/publons.com\/researcher\/2254619\/ondrej-vanek\/\">Publons<\/a>, or <a href=\"https:\/\/www.researchgate.net\/profile\/Ondej_Vank\">Research Gate<\/a>; (*) as the corresponding author.<\/p><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ol style=\"list-style-type:1\" class=\"wp-block-list\">\n<li>Bl\u00e1ha J., Sk\u00e1lov\u00e1 T., Kalouskov\u00e1 B., Sko\u0159epa O., Cmunt D., Grob\u00e1rov\u00e1 V., Pazicky S., Pol\u00e1chov\u00e1 E., Abreu C., Str\u00e1nsk\u00fd J., Koval&#8217; T., Du\u0161kov\u00e1 J., Zhao Y., Harlos K., Ha\u0161ek J., Dohn\u00e1lek J., <strong><u>Van\u011bk O.<\/u><\/strong>* (2022): Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse. <strong>Nat Commun 13, 5022.<\/strong><\/li>\n\n\n\n<li><strong><u>Van\u011bk O.<\/u><\/strong>*, Kalouskov\u00e1 B., Abreu C., Nejadebrahim S., Sko\u0159epa O. (2022): Natural killer cell-based strategies for immunotherapy of cancer. <strong>Adv Protein Chem Struct Biol 129, 91-133.<\/strong><\/li>\n\n\n\n<li>Kalouskov\u00e1 B., Sko\u0159epa O., Cmunt D., Abreu C., Krej\u010dov\u00e1 K., Bl\u00e1ha J., Sieglov\u00e1 I., Kr\u00e1l V., F\u00e1bry M., Pola R., Pechar M., <strong><u>Van\u011bk O.<\/u><\/strong>* (2021): Tumor marker B7-H6 bound to the coiled coil peptide-polymer conjugate enables targeted therapy by activating human natural killer cells. <strong>Biomedicines 9, 1597.<\/strong><\/li>\n\n\n\n<li>Sko\u0159epa O., Pa\u017eick\u00fd S., Kalouskov\u00e1 B., Bl\u00e1ha J., Abreu C., Je\u010dmen T., Ros\u016flek M., Fish A., Sedivy A., Harlos K., Dohn\u00e1lek J., Sk\u00e1lov\u00e1 T., <strong><u>Van\u011bk O.<\/u><\/strong>* (2020): Natural killer cell activation receptor NKp30 oligomerization depends on its N-glycosylation. <strong>Cancers 12, 1998.<\/strong><\/li>\n\n\n\n<li><strong><u>Van\u011bk O.<\/u><\/strong>*, Celadov\u00e1 P., Sko\u0159epa O., Bl\u00e1ha J., Kalouskov\u00e1 B., Dvorsk\u00e1 A., Pol\u00e1chov\u00e1 E., Pucholtov\u00e1 H., Kavan D., Pompach P., Hofbauerov\u00e1 K., Kopeck\u00fd V. Jr., Mesci, A., Voigt S., Carlyle J. R. (2019): Production of recombinant soluble dimeric C-type lectin-like receptors of rat natural killer cells. <strong>Sci Rep 9, 17836.<\/strong><\/li>\n\n\n\n<li>\u0160kerlov\u00e1 J., Bl\u00e1ha J., Pachl P., Hofbauerov\u00e1 K., Kuka\u010dka Z., Man P., Pompach P., Nov\u00e1k P., Otwinowski Z., Brynda J., <strong><u>Van\u011bk O.<\/u><\/strong>*, \u0158ez\u00e1\u010dov\u00e1 P.* (2018): Crystal structure of native \u03b2-N-acetylhexosaminidase isolated from <em>Aspergillus oryzae<\/em> sheds light onto its substrate specificity, high stability, and regulation by propeptide. <strong>FEBS J <\/strong><strong>285, 580-598.<\/strong><\/li>\n\n\n\n<li>Lynn G. M., Laga R., Darrah P. A., Ishizuka A. S., Balaci A. J., Dulcey A. E., Pechar M., Pola R., Gerner M. Y., Yamamoto A., Buechler C. R., Quinn K. M., Smelkinson M. G., <strong><u>Van\u011bk O.<\/u><\/strong>, Cawood R., Hills T., Vasalatiy O., Kastenm\u00fcller K., Francica J. R., Stutts L., Tom J. K., Ryu K. A., Esser-Kahn A. P., Etrych T., Fisher K. D., Seymour L. W., Seder R. A. (2015): <em>In vivo<\/em> characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity. <strong>Nat Biotechnol 33, 1201-1210.<\/strong><\/li>\n\n\n\n<li>Sk\u00e1lov\u00e1 T., Bl\u00e1ha J., Harlos K., Du\u0161kov\u00e1 J., Kova\u013e T., Str\u00e1nsk\u00fd J., Ha\u0161ek J., <strong><u>Van\u011bk O.<\/u><\/strong>, Dohn\u00e1lek J. (2015): Four crystal structures of human LLT1, a ligand for human NKR-P1, in varied glycosylation and oligomerization state. <strong>Acta Cryst D 71, 578-591.<\/strong><\/li>\n\n\n\n<li>Bl\u00e1ha J., Pachl P., Nov\u00e1k P., <strong><u>Van\u011bk O.<\/u><\/strong>* (2015): Expression and purification of soluble and stable ectodomain of natural killer cell receptor LLT1 through high-density transfection of suspension adapted HEK293S GnTI<sup>&#8211;<\/sup> cells. <strong>Protein Expr Purif 109, 7-13.<\/strong><\/li>\n\n\n\n<li>Sk\u00e1lov\u00e1 T., Kot\u00fdnkov\u00e1 K., Du\u0161kov\u00e1 J., Ha\u0161ek J., Koval T., Kolenko P., Nov\u00e1k P., Man P., Han\u010d P., <strong><u>Van\u011bk O.<\/u><\/strong>, Bezou\u0161ka K., Dohn\u00e1lek J. (2012): Mouse Clr-g, a ligand for NK cell activation receptor NKR-P1F: crystal structure and biophysical properties. <strong>J Immunol 189, 4881-4889.<\/strong><\/li>\n<\/ol>\n<\/div><\/div>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-right\"><em>Last updated 26. 12. 2024<\/em><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Head of the Laboratory of Structural Biochemistry of Immune Recognition at Charles University, Prague, Czech Republic Research profiles Research interests Vision for our research group We are a well-functioning research team pursuing exciting projects bringing health and prosperity! Education Selected special courses and workshops 2020 ARBRE-MOBIEU 2020 Plenary Meeting, Prague 24.-26. 2. 2020 (main organizer) [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-5430","page","type-page","status-publish","hentry"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"structimmuno","author_link":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/author\/structimmuno\/"},"uagb_comment_info":0,"uagb_excerpt":"Head of the Laboratory of Structural Biochemistry of Immune Recognition at Charles University, Prague, Czech Republic Research profiles Research interests Vision for our research group We are a well-functioning research team pursuing exciting projects bringing health and prosperity! Education Selected special courses and workshops 2020 ARBRE-MOBIEU 2020 Plenary Meeting, Prague 24.-26. 2. 2020 (main organizer)&hellip;","_links":{"self":[{"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/pages\/5430","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/comments?post=5430"}],"version-history":[{"count":4,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/pages\/5430\/revisions"}],"predecessor-version":[{"id":7393,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/pages\/5430\/revisions\/7393"}],"wp:attachment":[{"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/media?parent=5430"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}