{"id":6739,"date":"2022-09-19T20:39:28","date_gmt":"2022-09-19T20:39:28","guid":{"rendered":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/?p=6739"},"modified":"2025-05-28T17:31:21","modified_gmt":"2025-05-28T17:31:21","slug":"our-new-article-featured-on-faculty-website","status":"publish","type":"post","link":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/our-new-article-featured-on-faculty-website\/","title":{"rendered":"Our new article is featured on the Faculty of Science website!"},"content":{"rendered":"\n<p><p style=\"text-align: justify;\"><a href=\"https:\/\/natur.cuni.cz\/en\/chemistry\/departments-and-work-places\/department-of-biochemistry\/about-department\/news\/7784-from-the-atom-to-nk-cell-the-story-of-an-unexpected-protein-structure\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">From the atom to NK cell: the story of an unexpected protein structure<\/mark><\/strong><\/a> is the name of an article featured on the front page of the Faculty of Science describing our path to a new publication in the prestigious journal Nature Communications.<\/p><\/p>\n\n\n\n<p><p style=\"text-align: justify;\">The article describes the journey from the very beginning, tells about the obstacles surpassed and the hard work of the people involved, and drags you into exciting research. Research that has resulted in a publication named <a rel=\"noreferrer noopener\" href=\"https:\/\/www.nature.com\/articles\/s41467-022-32577-6\" data-type=\"URL\" data-id=\"https:\/\/www.nature.com\/articles\/s41467-022-32577-6\" target=\"_blank\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse<\/mark><\/strong><\/a>.<\/p><\/p>\n\n\n\n<figure class=\"wp-block-pullquote\"><blockquote><p><em>&#8220;The result was quite unexpected and interesting. One wonders at that moment whether this is just an artifact of the crystal or whether such a structure really exists on the cell surface.&#8221;<\/em><\/p><cite>RNDr. Ond\u0159ej Van\u011bk, Ph.D.<\/cite><\/blockquote><\/figure>\n\n\n\n<p><p style=\"text-align: justify;\">In this study, the research team led by Dr. Ond\u0159ej Van\u011bk from the Department of Biochemistry, Faculty of Science, Charles University, and his colleagues from the Institute of Biotechnology of the Czech Academy of Sciences in the center BIOCEV have discovered the structure of a protein complex involved in recognizing cancerous cells and further studied the fashion in which these proteins interact. <\/p><\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-gallery alignwide has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"748\" height=\"730\" data-id=\"6744\" src=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_4.png\" alt=\"\" class=\"wp-image-6744\" srcset=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_4.png 748w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_4-300x293.png 300w\" sizes=\"auto, (max-width: 748px) 100vw, 748px\" \/><figcaption class=\"wp-element-caption\"><a href=\"https:\/\/www.natur.cuni.cz\/eng\/aktuality\/from-the-atom-to-nk-cell-the-story-of-an-unexpected-protein-structure?set_language=en\">https:\/\/www.natur.cuni.cz\/eng\/aktuality\/from-the-atom-to-nk-cell-the-story-of-an-unexpected-protein-structure?set_language=en<\/a><\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"2560\" data-id=\"6746\" src=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/IMG_20220913_134525-2-kopie-edited-scaled.jpg\" alt=\"\" class=\"wp-image-6746\" srcset=\"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/IMG_20220913_134525-2-kopie-edited-scaled.jpg 2560w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/IMG_20220913_134525-2-kopie-edited-300x300.jpg 300w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/IMG_20220913_134525-2-kopie-edited-1024x1024.jpg 1024w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/IMG_20220913_134525-2-kopie-edited-150x150.jpg 150w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/IMG_20220913_134525-2-kopie-edited-768x768.jpg 768w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/IMG_20220913_134525-2-kopie-edited-1536x1536.jpg 1536w, https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/IMG_20220913_134525-2-kopie-edited-2048x2048.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><figcaption class=\"wp-element-caption\">The laboratory leader, RNDr. Ond\u0159ej Van\u011bk, Ph.D.<\/figcaption><\/figure>\n<\/figure>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><p style=\"text-align: justify;\">The new publication is success possible only thanks to the efficient collaboration with several other research teams:<br>\u2013 Tereza Sk\u00e1lov\u00e1,&nbsp;Jan Str\u00e1nsk\u00fd,&nbsp;Tom\u00e1\u0161 Kova\u013e,&nbsp;Jarmila Du\u0161kov\u00e1,&nbsp;Jind\u0159ich Ha\u0161ek&nbsp;&amp;&nbsp;Jan Dohn\u00e1lek (Institute of Biotechnology, The Czech Academy of Sciences, BIOCEV Centre, Vestec, Czech Republic)<br>\u2013 Val\u00e9ria Grob\u00e1rov\u00e1 (Department of Cell Biology, Faculty of Science, Charles University, Prague, Czech Republic)<br>\u2013 Yuguang Zhao&nbsp;&amp;&nbsp;Karl Harlos (Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom)<\/p><\/p>\n\n\n\n<p>Thank you all!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>From the atom to NK cell: the story of an unexpected protein structure is the name of an article featured on the front page of the Faculty of Science describing our path to a new publication in the prestigious journal Nature Communications. The article describes the journey from the very beginning, tells about the obstacles [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":6752,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[16],"tags":[],"class_list":["post-6739","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications"],"uagb_featured_image_src":{"full":["https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_5.png",752,501,false],"thumbnail":["https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_5-150x150.png",150,150,true],"medium":["https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_5-300x200.png",300,200,true],"medium_large":["https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_5.png",640,426,false],"large":["https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_5.png",640,426,false],"1536x1536":["https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_5.png",752,501,false],"2048x2048":["https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-content\/uploads\/2022\/09\/news-article_5.png",752,501,false]},"uagb_author_info":{"display_name":"structimmuno","author_link":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/author\/structimmuno\/"},"uagb_comment_info":0,"uagb_excerpt":"From the atom to NK cell: the story of an unexpected protein structure is the name of an article featured on the front page of the Faculty of Science describing our path to a new publication in the prestigious journal Nature Communications. The article describes the journey from the very beginning, tells about the obstacles&hellip;","_links":{"self":[{"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/posts\/6739","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/comments?post=6739"}],"version-history":[{"count":2,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/posts\/6739\/revisions"}],"predecessor-version":[{"id":7730,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/posts\/6739\/revisions\/7730"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/media\/6752"}],"wp:attachment":[{"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/media?parent=6739"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/categories?post=6739"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/biochem\/structimmuno\/wp-json\/wp\/v2\/tags?post=6739"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}