{"id":4843,"date":"2021-01-19T15:23:42","date_gmt":"2021-01-19T14:23:42","guid":{"rendered":"https:\/\/ukazky.euweb.cz\/?page_id=4843"},"modified":"2023-10-19T09:06:29","modified_gmt":"2023-10-19T09:06:29","slug":"home1","status":"publish","type":"page","link":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/","title":{"rendered":"Home"},"content":{"rendered":"<div><ss3-force-full-width data-overflow-x=\"html\" data-horizontal-selector=\"html\"><div class=\"n2-section-smartslider fitvidsignore aol\" data-ssid=\"2\" tabindex=\"0\" role=\"region\" aria-label=\"Slider\"><div id=\"n2-ss-2-align\" class=\"n2-ss-align\"><div class=\"n2-padding\"><div id=\"n2-ss-2\" data-creator=\"Smart Slider 3\" data-responsive=\"fullwidth\" class=\"n2-ss-slider n2-ow n2-has-hover n2notransition  \">\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n<div class=\"n2-ss-slider-wrapper-outside\" style=\"grid-template-rows:1fr auto\"><div class=\"n2-ss-slider-wrapper-inside\">\n        <div class=\"n2-ss-slider-1 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tabindex=\"-1\">Slider 2<\/div><div class=\"n2-ss-layers-container n2-ss-slide-limiter n2-ow\"><div class=\"n2-ss-layer n2-ow n-uc-tYSFEFc8PWsJ\" data-sstype=\"slide\" data-pm=\"default\"><div class=\"n2-ss-layer n2-ow aol n-uc-8YnI29t2x6yj\" data-pm=\"default\" data-sstype=\"content\" data-hasbackground=\"0\"><div class=\"n2-ss-section-main-content n2-ss-layer-with-background n2-ss-layer-content n2-ow n-uc-8YnI29t2x6yj-inner\"><div class=\"n2-ss-layer n2-ow n-uc-H6oDlhlwKzN2\" data-pm=\"normal\" data-sstype=\"layer\"><div id=\"n2-ss-2item1\" class=\"n2-font-d0b983ab807da9ce9f5c6774c4bf3cc3-hover n2-style-a806f082b4f12aab349556997fbaa1f5-heading   n2-ss-item-content n2-ss-text n2-ow\" style=\"display:block;\">Host &#8211; Pathogen Interactions<\/div><\/div><div class=\"n2-ss-layer n2-ow n-uc-uRqMIs4ZRpGu n2-ss-layer--auto\" data-pm=\"normal\" data-sstype=\"layer\"><div class=\"n2-ss-button-container n2-ss-item-content n2-ow n2-font-fcb7ef0bb429381456f9848184f6449b-link  n2-ss-nowrap 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class=\"n2-font-d0b983ab807da9ce9f5c6774c4bf3cc3-hover n2-style-a806f082b4f12aab349556997fbaa1f5-heading   n2-ss-item-content n2-ss-text n2-ow\" style=\"display:block;\">Shaping adaptive immune response by antigen presentation<\/div><\/div><div class=\"n2-ss-layer n2-ow n-uc-yIf910Wo3XRK n2-ss-layer--auto\" data-pm=\"normal\" data-sstype=\"layer\"><div class=\"n2-ss-button-container n2-ss-item-content n2-ow n2-font-fcb7ef0bb429381456f9848184f6449b-link  n2-ss-nowrap n2-ss-button-container--non-full-width\"><a class=\"n2-style-385c3b0fc68cc4a096185e0f3bfe4091-heading  n2-ow \" href=\".\/publications\"><div><div>Read more<\/div><\/div><\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div data-slide-duration=\"0\" data-id=\"3\" data-slide-public-id=\"3\" aria-hidden=\"true\" data-title=\"Slider 1\" class=\"n2-ss-slide n2-ow  n2-ss-slide-3\"><div role=\"note\" class=\"n2-ss-slide--focus\" tabindex=\"-1\">Slider 1<\/div><div class=\"n2-ss-layers-container n2-ss-slide-limiter n2-ow\"><div class=\"n2-ss-layer n2-ow n-uc-15S6UcoSnaUi\" data-sstype=\"slide\" data-pm=\"default\"><div class=\"n2-ss-layer n2-ow aol n-uc-9QOfcX2BREDt\" data-pm=\"default\" data-sstype=\"content\" data-hasbackground=\"0\"><div class=\"n2-ss-section-main-content n2-ss-layer-with-background n2-ss-layer-content n2-ow n-uc-9QOfcX2BREDt-inner\"><div class=\"n2-ss-layer n2-ow n-uc-e7Y9vE9yLOEd\" data-pm=\"normal\" data-sstype=\"layer\"><div id=\"n2-ss-2item5\" class=\"n2-font-d0b983ab807da9ce9f5c6774c4bf3cc3-hover n2-style-a806f082b4f12aab349556997fbaa1f5-heading   n2-ss-item-content n2-ss-text n2-ow\" style=\"display:block;\">Faculty of Science, Charles University<\/div><\/div><div class=\"n2-ss-layer n2-ow n-uc-H7IDpfpDOc5y n2-ss-layer--auto\" data-pm=\"normal\" data-sstype=\"layer\"><div class=\"n2-ss-button-container n2-ss-item-content n2-ow n2-font-fcb7ef0bb429381456f9848184f6449b-link  n2-ss-nowrap n2-ss-button-container--non-full-width\"><a class=\"n2-style-385c3b0fc68cc4a096185e0f3bfe4091-heading  n2-ow \" href=\"https:\/\/www.natur.cuni.cz\/eng\"><div><div>Read more<\/div><\/div><\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div>                    <\/div>\n\n                                    <\/div>\n            <\/div>\n        <\/div>\n        <div class=\"n2-ss-slider-controls n2-ss-slider-controls-absolute-left-center\"><div style=\"--widget-offset:px;\" class=\"n2-ss-widget n2-style-c31c7e0464fcc560d67fa0a16efb2dbb-heading nextend-arrow n2-ow-all nextend-arrow-previous  nextend-arrow-animated-fade\" data-hide-mobileportrait=\"1\" id=\"n2-ss-2-arrow-previous\" role=\"button\" aria-label=\"previous arrow\" tabindex=\"0\"><img loading=\"lazy\" decoding=\"async\" width=\"32\" height=\"32\" class=\"skip-lazy\" data-skip-lazy=\"1\" 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width=\"32\" height=\"32\" class=\"skip-lazy\" data-skip-lazy=\"1\" src=\"data:image\/svg+xml;base64,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\" alt=\"next arrow\"><\/div><\/div><div class=\"n2-ss-slider-controls n2-ss-slider-controls-absolute-center-bottom\"><div class=\"n2-ss-widget nextend-bar nextend-bar-horizontal n2-ss-widget-hidden n2-ow-all\" style=\"text-align: center;width:100%;\"><div class=\"n2-style-262439a2543e3b0e82e53b7b16f68f07-simple \"><span class=\"n2-font-9d826489b351b9c84832aefd0791c401-simple \">&nbsp;<\/span><\/div><\/div><\/div><\/div><div class=\"n2-ss-slider-controls n2-ss-slider-controls-below\"><div style=\"--widget-offset:px;\" class=\"n2-ss-widget n2-ss-control-bullet n2-ow-all n2-ss-control-bullet-horizontal\"><div class=\"n2-style-92baf0a463a4bda579d2bd95782e0fa5-simple  nextend-bullet-bar n2-bar-justify-content-center\" role=\"group\" aria-label=\"Choose slide to display.\"><div class=\"n2-bullet n2-style-d5c7186135a811450604231984a67713-dot \" style=\"visibility:hidden;\"><\/div><\/div><\/div><\/div><\/div><\/div><ss3-loader><\/ss3-loader><\/div><\/div><div class=\"n2_clear\"><\/div><\/div><\/ss3-force-full-width><\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center page-title-home\" id=\"welcome-to-the-laboratory-for-evolutionary-and-ecological-immunology\">Laboratory of Microbial Immunology<\/h2>\n\n\n\n<p class=\"has-text-align-center\">Our focus lies in unraveling the intricate cell fate decisions guided by antigen presentation within the immune system. We delve into the realm of antigen-presenting cells, exploring their biology, interactions with various cell types, and the intricate mechanisms they employ to modulate T-cell responses, be it in response to pathogens, commensal microorganisms, or self-structures. Our overarching goal is to gain a comprehensive understanding of the underlying mechanisms that give rise to immune-related pathologies. By doing so, we aim to pave the way for the development of more effective treatment strategies in the future.<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group blok_wide has-background\" style=\"background-color:#f3f3f3\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<h3 class=\"wp-block-heading has-text-align-center box_homepage\" id=\"research-area\">Research area<\/h3>\n\n\n\n<p class=\"has-text-align-center\">Host-pathogen interactions, antigen presenting cells, adaptive immunity.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-buttons important-btns is-horizontal is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-499968f5 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button important-btn is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color has-background wp-element-button\" href=\".\/research\/\" style=\"color:#cd3044;background-color:#f3f3f3\">OUR RESEARCH<\/a><\/div>\n\n\n\n<div class=\"wp-block-button important-btn important-btn22 is-style-outline is-style-outline--2\"><a class=\"wp-block-button__link has-text-color has-background wp-element-button\" href=\".\/publications\/\" style=\"color:#cd3044;background-color:#f3f3f3\">PUBLICATIONS<\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<h2 class=\"wp-block-heading has-text-align-center\" id=\"news\">News<\/h2>\n\n\n<ul class=\"wp-block-latest-posts__list is-grid columns-3 has-dates aligncenter wp-block-latest-posts\"><li><div class=\"wp-block-latest-posts__featured-image\"><a href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/honza-presented-our-work-on-the-conference\/\" aria-label=\"Honza presented our work on the conference\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"662\" src=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2024\/06\/Jana-seefeld-990x1024.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2024\/06\/Jana-seefeld-990x1024.jpg 990w, https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2024\/06\/Jana-seefeld-290x300.jpg 290w, https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2024\/06\/Jana-seefeld-768x795.jpg 768w, https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2024\/06\/Jana-seefeld.jpg 1291w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/honza-presented-our-work-on-the-conference\/\">Honza presented our work on the conference<\/a><time datetime=\"2026-01-30T10:57:29+00:00\" class=\"wp-block-latest-posts__post-date\">January 30, 2026<\/time><div class=\"wp-block-latest-posts__post-excerpt\">Honza presented the research work of our laboratory at the Harald von Boehmer Midwinter Conference\u2026 <a class=\"wp-block-latest-posts__read-more\" href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/honza-presented-our-work-on-the-conference\/\" rel=\"noopener noreferrer\">Read more<span class=\"screen-reader-text\">: Honza presented our work on the conference<\/span><\/a><\/div><\/li>\n<li><div class=\"wp-block-latest-posts__featured-image\"><a href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/grant-alert-gacr\/\" aria-label=\"Grant alert &#8211; GA\u010cR\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"322\" src=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2025\/12\/farnsworth.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2025\/12\/farnsworth.jpg 600w, https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2025\/12\/farnsworth-300x161.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/grant-alert-gacr\/\">Grant alert &#8211; GA\u010cR<\/a><time datetime=\"2025-12-02T10:50:52+00:00\" class=\"wp-block-latest-posts__post-date\">December 2, 2025<\/time><div class=\"wp-block-latest-posts__post-excerpt\">The Czech Science Foundation (GA\u010cR) has announced the results of\u00a0its Standard Grant Scheme for 2025.\u2026 <a class=\"wp-block-latest-posts__read-more\" href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/grant-alert-gacr\/\" rel=\"noopener noreferrer\">Read more<span class=\"screen-reader-text\">: Grant alert &#8211; GA\u010cR<\/span><\/a><\/div><\/li>\n<li><div class=\"wp-block-latest-posts__featured-image\"><a href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/honza-visited-cro-laborator\/\" aria-label=\"Honza visited &#8220;\u010cRo: Laborato\u0159&#8221;\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"359\" src=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2026\/02\/3e9b03b7ecc6d74d2c7c9e88bc64cd1e-1024x575.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2026\/02\/3e9b03b7ecc6d74d2c7c9e88bc64cd1e-1024x575.jpg 1024w, https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2026\/02\/3e9b03b7ecc6d74d2c7c9e88bc64cd1e-300x168.jpg 300w, https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2026\/02\/3e9b03b7ecc6d74d2c7c9e88bc64cd1e-768x431.jpg 768w, https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-content\/uploads\/2026\/02\/3e9b03b7ecc6d74d2c7c9e88bc64cd1e.jpg 1040w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/honza-visited-cro-laborator\/\">Honza visited &#8220;\u010cRo: Laborato\u0159&#8221;<\/a><time datetime=\"2025-11-08T10:41:00+00:00\" class=\"wp-block-latest-posts__post-date\">November 8, 2025<\/time><div class=\"wp-block-latest-posts__post-excerpt\">Honza was invited twice this year to &#8216;\u010cRo: Laborato\u0159,&#8217; a radio podcast that explains current\u2026 <a class=\"wp-block-latest-posts__read-more\" href=\"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/honza-visited-cro-laborator\/\" rel=\"noopener noreferrer\">Read more<span class=\"screen-reader-text\">: Honza visited &#8220;\u010cRo: Laborato\u0159&#8221;<\/span><\/a><\/div><\/li>\n<\/ul><\/div><\/div>\n\n\n\n<div style=\"height:1px\" aria-hidden=\"true\" class=\"wp-block-spacer news-line\"><\/div>\n\n\n\n<div class=\"wp-block-buttons button-news is-horizontal is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-499968f5 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline important-btn is-style-outline--3\"><a class=\"wp-block-button__link has-vivid-red-color has-white-background-color has-text-color has-background wp-element-button\" href=\"http:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/news\/\">MORE NEWS<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Laboratory of Microbial Immunology Our focus lies in unraveling the intricate cell fate decisions guided by antigen presentation within the immune system. We delve into the realm of antigen-presenting cells, exploring their biology, interactions with various cell types, and the intricate mechanisms they employ to modulate T-cell responses, be it in response to pathogens, commensal [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-4843","page","type-page","status-publish","hentry"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/author\/admin\/"},"uagb_comment_info":0,"uagb_excerpt":"Laboratory of Microbial Immunology Our focus lies in unraveling the intricate cell fate decisions guided by antigen presentation within the immune system. We delve into the realm of antigen-presenting cells, exploring their biology, interactions with various cell types, and the intricate mechanisms they employ to modulate T-cell responses, be it in response to pathogens, commensal&hellip;","_links":{"self":[{"href":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-json\/wp\/v2\/pages\/4843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-json\/wp\/v2\/comments?post=4843"}],"version-history":[{"count":12,"href":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-json\/wp\/v2\/pages\/4843\/revisions"}],"predecessor-version":[{"id":5933,"href":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-json\/wp\/v2\/pages\/4843\/revisions\/5933"}],"wp:attachment":[{"href":"https:\/\/web.natur.cuni.cz\/cellbiol\/dobeslab\/wp-json\/wp\/v2\/media?parent=4843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}