Our recent paper introducing a new cell line tool for improved diagnostics of Alagille syndrome Jag1 and Notch2 variants in Human Genetics is now out. Thanks to Daniel, Fabio and everyone in the Masek Lab who contributed to the LNA cell system—great work by the whole team. Special thanks to the the clinicians led by […]

Cells talk to one another all the time using cascades of protein interactions. Now, we know for quite some time that proteins from different cascades can interact with each other. It’s called crosstalk. But doesn’t it defy the logic of clear communication channels between cells? 🧐Together with the team of Jakub Harnoš, we compiled available […]

Big thanks to Hana and Eliska for their time with our lab and successful defense of their master’s theses! Good luck pursuing your PhD projects! At the same time, we welcome Vimal, our new PhD student, and Sara, Eli, and Alex new master’s and bachelor students. We are happy to have you onboard!

Honored to receive these t-shirts, learning the powerful story of Roberta Smith from the Alagille Syndrome Alliance behind them. 💛 www.linkedin.com/in/roberta-s…

Very proud of our PhD student Anna, and grateful to GAUK, for funding her 2-year project on 3D visualisation of liver mesenchyme under cholestatic condition. Well deserved!

Grateful for the GAČR funding we received to study how mesenchyme contributes to liver development. to our liver team Daniel, Anna, and Eliška who worked so hard on the preliminary data.

Beyond happy to share our newest research just published in EMBO Molecular Medicine. Read a tweetorial here or a Charles University Press release here to find out more.

Big congratulations to Fabio! His project was selected for a talk at this year’s Notch GRC conference! https://www.grc.org/notch-signaling-in-development-regeneration-and-disease-conference/2024/ Great collaboration with https://www.sci.muni.cz/ofiz/en/harnos-lab-2/ .

Teodor successfully defended his experimental bachelor thesis on Notch1 GSK3b crosstalk, huge congratulations!

Happy to share the new review in Trends in Molecular Medicine spearheaded by Brabek Lab, where we contributed with our DevCellBiol expertise. Educate Not Kill 🙂 https://doi.org/10.1016/j.ceb.2023.102302