Cecilia Sahlgren Ph.D.
Professor, Faculty of Science and Engineering, Cell Biology,
Åbo Akademi University, Finland
Cecilia is currently a Professor in Cell Biology at Åbo Akademi University, Finland, and a part-time professor in the Biomedical Engineering department at the Eindhoven University of Technology, the Netherlands. She focuses her research on understanding how the coordination of cells through molecular cell signaling pathways is crucial for forming functional tissues. Her Lab, CellFate Lab, now tries to answer the following research questions:
~ How are signaling mechanisms regulating cell fate decisions based on input from cell-autonomous mechanisms and the environment?
~ How do these mechanisms influence cell fate and how do deregulated mechanisms link to disease?
~ How can cell signaling be modulated for therapeutic purposes to control cell fate in cancer and regenerative therapy?
– Engineering tissue morphogenesis: taking it up a Notch
– An N-glycan on the C2 domain of JAGGED1 is important for Notch activation
Website: CellFate Lab
Jesse Veenvliet Ph.D.
Research Group Leader, Max Planck Institute of Molecular Cell Biology and Genetics
Jesse is currently, is currently a Group Leader at the Max Plank Institute of Molecular cell biology and genetics. Jess Veenvliet Lab is focused on ”Stembryogenesis”, striving to understand how embryos build themselves by reconstructing development in a dish. Among his biological questions are.
~ Which cell-cell, cell-matrix and tissue-tissue interactions drive mammalian embryo architecture?
~ How are form and fate coordinated?
~ How is developmental variability controlled?
To answer this unanswered question his lab is using pluripotent-stem-cell-derived stembryos (embryonic organoids).
– Carnegie in 4D? Stem-cell-based models of human embryo development
– Hypoxia induces an early primitive streak signature, enhancing spontaneous elongation and lineage representation in gastruloids
Website: Jess Veenvliet Lab
Twitter: jvveenvliet