Laboratory Equipment

Confocal microscopes

The Leica TCS SP8 is a high-end inverted confocal microscope designed for the advanced fluorescence imaging of fixed and live biological samples. It offers outstanding sensitivity, resolution, and versatility suitable for various applications, including cell biology, developmental biology, neurobiology, plant sciences, and more.

Manufacturer: Leica Microsystems
Model: Leica TCS SP8 (inverted)
Location: room S39


The Zeiss LSM 880 NLO is an advanced confocal microscope featuring single-photon and multiphoton excitation capabilities. Ideal for high-resolution, deep-tissue imaging, it provides outstanding sensitivity and spectral flexibility, supporting extensive applications in life sciences, particularly neurobiology, developmental biology, and cell biology.

Manufacturer: Carl Zeiss AG
Model: LSM 880 NLO (Inverted, Multiphoton)
Location: room S39


The inverted confocal Raman microscope WITec Alpha300 Ri is equipped with a
532 nm laser and a highly sensitive Andor detection system, designed for confocal micro-Raman spectroscopy in the visible spectral range. Signal detection is based on a cooled CCD camera optimized for the
UV–VIS region, providing very high detection efficiency already around 400 nm, which enables reliable acquisition of even very weak Raman signals.

The microscope was co-financed as part of the project “Development of Infrastructure for Doctoral Programs at Charles University” with registration number CZ.02.01.01/00/22_012/0005514 and is intended for teaching and student training in modern optical and spectroscopic methods.

Manufacturer: OXFORD Instruments
Model: WITec Alpha300 Ri (inverted)
Location: room S47
Phone: +420 22195 1061


Wide-field microscopes

The Nikon ECLIPSE Ti2 is an advanced inverted wide-field microscope renowned for its exceptional optical performance, expansive 25mm field of view (FOV), and versatility in accommodating a wide range of imaging applications, from routine cell culture observations to complex live-cell imaging studies using the advanced JOBs module.

Manufacturer: Nikon Instruments Inc.
Model: Nikon ECLIPSE Ti2-E
Location: room p108 (floor)
Phone: +420 22195 1033


The Zeiss Axio Scan.Z1 is a fully automated high-throughput slide scanner designed for rapid, high-quality, and reliable digitization of large numbers of histological, cytological slides, and other samples. The system is ideal for high-volume data projects, high-content screening, and routine image digitization for sharing and analysis.

Manufacturer: Carl Zeiss
Model: Axio Scan.Z1 (Automated Upright Slide Scanner)
Location: room p108 (floor)
Phone: +420 22195 1033


Stereo microscopes


Lightsheet microscopes


Super-resolution microscopes

The Zeiss Elyra PS.1 microscope utilizes technologies of structured illumination (SIM) and precise localization (PALM/STORM) to overcome the so-called diffraction barrier, which limits conventional light microscopy to a resolution of around 200 nm. Nanoscopy allows us to observe structures with 2-3x higher resolution with SIM and up to 5 nm with localization microscopy. The microscope utilizes TIRF (Total Internal Reflection Fluorescence) technology to enhance the signal-to-noise ratio in the space immediately adjacent to the cover glass. A set of high-quality lasers and cameras enables us to create exceptional super-resolution images.

Manufacturer: Carl Zeiss Microscopy
Model: Zeiss Elyra PS.1 (inverted)
Location: room S47
Phone: +420 221 951 060


Other advanced equipment