Our research featured on the JCI Insight journal’s cover

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Our research has been featured on the front cover of the JCI Insight journal (Volume 9, Issue 18, published on 24th September 2024). The image highlights our work on IL-2 immunocytokines, showcasing their potential for targeted immune modulation. This recognition underscores the significance of our findings in cytokine engineering and immune therapy.

This study is part of a Czech Science Foundation-funded project on IL-2 immunocytokines, which recently received an “excellent” rating. The research contributes to the growing field of precision immunotherapy, focusing on improving IL-2 delivery to immune effector cells for safer and more effective cancer treatment.

Leonard, E. K.; Tomala, J.; Gould, J. R.; Leff, M. I.; Lin, J.-X.; Li, P.; Porter, M. J.; Johansen, E. R.; Thompson, L.; Cao, S. D.; Hou, S.; Henclova, T.; Huliciak, M.; Sargunas, P. R.; Fabilane, C. S.; Vaněk, O.; Kovar, M.; Schneider, B.; Raimondi, G.; Leonard, W. J.; Spangler, J. B.: Engineered Cytokine/Antibody Fusion Proteins Improve IL-2 Delivery to pro-Inflammatory Cells and Promote Antitumor Activity. JCI Insight 2024;9(18):e173469. https://doi.org/10.1172/jci.insight.173469.