Publications

Markos, A.; Voltrova, S.; Motornov, V.; Tichy, D.; Klepetářová, B.; Beier, P. Stereoselective Synthesis of (Z)-beta-Enamido Triflates and Fluorosulfonates from N-Fluoroalkylated Triazoles. Chemistry-a European Journal 2019, 25 (32), 7640-7644 DOI: 10.1002/chem.201901632.

Markos, A.; Voltrova, S.; Motornov, V.; Tichy, D.; Klepetářová, B.; Beier, P. Stereoselective Synthesis of (Z)-beta-Enamido Triflates and Fluorosulfonates from N-Fluoroalkylated Triazoles. Chemistry-a European Journal 2019, 25 (32), 7640-7644 DOI: 10.1002/chem.201901632.

Malnuit, V.; Smolen, S.; Tichý, M.; Slavětínská, L. Poštová; Hocek, M. Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6-(Thiophen-2-yl)-7-fluoro-7-deazapurine. European Journal of Organic Chemistry 2019, 2019 (31-32), 5409-5423 DOI: 10.1002/ejoc.201900509.

Hocek, M.; Matyašovský, J. 2-Substituted 2 '-deoxyinosine 5 '-triphosphates as substrates for polymerase synthesis of minor-groove-modified DNA and effects on restriction endonuclease cleavage. Organic and Biomolecular Chemistry 2020, 18 (2), 255-262 DOI: 10.1039/c9ob02502b.

Drastík, M.; Holas, O.; Hroch, M.; Hutníková, M.; Kašpar, M.; Kudová, E.; Mičuda, S.; Pandey, A. V.; Pávek, P.; Smutný, T.; et al. 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism. Journal of Steroid Biochemistry and Molecular Biology 2020, 202 (September), nestránkováno DOI: 10.1016/j.jsbmb.2020.105702.

Bednářová, E.; Kotora, M.; Malatinec, Š. Applications of Bolm's Ligand in Enantioselective Synthesis. Molecules 2020, 25 (4), nestránkováno DOI: 10.3390/molecules25050958.

Brynda, J.; Fanfrlík, J.; Hadzima, M.; Hánová, I.; Horn, M.; Houštecká, R.; Lepšík, M.; Majer, P.; Mareš, M.; Mertlíková-Kaiserová, H.; et al. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of Medicinal Chemistry 2020, 63 (4), 1576-1596 DOI: 10.1021/acs.jmedchem.9b01351.

Brynda, J.; Fanfrlík, J.; Hadzima, M.; Hánová, I.; Horn, M.; Houštecká, R.; Lepšík, M.; Majer, P.; Mareš, M.; Mertlíková-Kaiserová, H.; et al. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of Medicinal Chemistry 2020, 63 (4), 1576-1596 DOI: 10.1021/acs.jmedchem.9b01351.

Brynda, J.; Fanfrlík, J.; Hadzima, M.; Hánová, I.; Horn, M.; Houštecká, R.; Lepšík, M.; Majer, P.; Mareš, M.; Mertlíková-Kaiserová, H.; et al. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of Medicinal Chemistry 2020, 63 (4), 1576-1596 DOI: 10.1021/acs.jmedchem.9b01351.

Báječný, M.; Beneš, J.; Czernek, J.; Dunlop, D.; Francová, P.; Groborz, O.; Heizer, T.; Hobza, P.; Hrubý, M.; Kolouchová, K.; et al. Chelating Polymers for Hereditary Hemochromatosis Treatment. Macromolecular Bioscience 2020, 20 (12), nestránkováno DOI: 10.1002/mabi.202000254.

Kasireddy, S. Reddy; Míšek, J.; Nosek, V.; Tarallo, V. Development of a simple high-throughput assay for directed evolution of enantioselective sulfoxide reductases. Chemical Communications 2020, 56 (40), 5386-5388 DOI: 10.1039/d0cc01660h.

Kadaník, M.; Kočovský, P.; Kuneš, J.; Maříková, J.; Matouš, P.; Pour, M.; Růžička, A.; Timoracký, M. Nucleophile-assisted cyclization of beta-propargylamino acrylic compounds catalyzed by gold(I): a rapid construction of multisubstituted tetrahydropyridines and their fused derivatives. Organic Chemistry Frontiers 2020, 7 (21), 3356-3367 DOI: 10.1039/d0qo00653j.

Kadaník, M.; Kočovský, P.; Kuneš, J.; Maříková, J.; Matouš, P.; Pour, M.; Růžička, A.; Timoracký, M. Nucleophile-assisted cyclization of beta-propargylamino acrylic compounds catalyzed by gold(I): a rapid construction of multisubstituted tetrahydropyridines and their fused derivatives. Organic Chemistry Frontiers 2020, 7 (21), 3356-3367 DOI: 10.1039/d0qo00653j.

Beier, P.; Klimánková, I.; Košťál, V.; Motornov, V.; Tichy, D. Preparation of 1-Azido-2-Bromo-1,1,2,2-Tetrafluoroethane and Its Use in the Synthesis of N-Fluoroalkylated Nitrogen Heterocycles. Journal of Organic Chemistry 2020, 85 (17), 11482-11489 DOI: 10.1021/acs.joc.0c01610.

Bastien, G.; Císařová, I.; Dračínský, M.; Hurtado, C. Santos; Kaleta, J.; Mašát, M.; Rogers, C. T.; Rončević, I.; Štoček, J. Radek. Regular Two-Dimensional Arrays of Surface-Mounted Molecular Switches: Switching Monitored by UV-vis and NMR Spectroscopy. Journal of the American Chemical Society 2020, 142 (20), 9337-9351 DOI: 10.1021/jacs.0c01753.

Abdelsayed, M. M.; A. Chamberlin, R.; Chizzolini, F.; Kasireddy, S. Reddy; Luptak, A.; Míšek, J.; Passalacqua, L. F. M.; Rotstan, K. A. Regulation of mRNA translation by a photoriboswitch. eLife 2020, 9 (February 2020), nestránkováno DOI: 10.7554/eLife.51737.

Brynda, J.; Das, V.; Dvořanová, J.; Džubák, P.; Anwar, S. El; Fábry, M.; Grüner, B.; Gurska, S.; Hajdúch, M.; Havránek, M.; et al. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. European Journal of Medicinal Chemistry 2020, 200 (August), nestránkováno DOI: 10.1016/j.ejmech.2020.112460.

Brynda, J.; Das, V.; Dvořanová, J.; Džubák, P.; Anwar, S. El; Fábry, M.; Grüner, B.; Gurska, S.; Hajdúch, M.; Havránek, M.; et al. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. European Journal of Medicinal Chemistry 2020, 200 (August), nestránkováno DOI: 10.1016/j.ejmech.2020.112460.

Gallardo, P. Güixens; Hocek, M.; Hof, M.; Humpolickova, J.; Jurkiewicz, P.; Kraus, T.; Miclea, S. Paul; Pohl, R. Thiophene-linked tetramethylbodipy-labeled nucleotide for viscosity-sensitive oligonucleotide probes of hybridization and protein-DNA interactions. Organic and Biomolecular Chemistry 2020, 18 (5), 912-919 DOI: 10.1039/c9ob02634g.

Albiñana, C. Berenguer; Brynda, J.; Fanfrlík, J.; Flieger, M.; Hodek, J.; Karlukova, E.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Majer, P.; et al. Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors. European Journal of Medicinal Chemistry 2020, 208 (December), nestránkováno DOI: 10.1016/j.ejmech.2020.112754.

Albiñana, C. Berenguer; Brynda, J.; Fanfrlík, J.; Flieger, M.; Hodek, J.; Karlukova, E.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Majer, P.; et al. Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors. European Journal of Medicinal Chemistry 2020, 208 (December), nestránkováno DOI: 10.1016/j.ejmech.2020.112754.

Benýšek, J.; Krečmerová, M.; Matoušová, M.; Kaiserová, H. Mertlíkov; Otmar, M.; Pohl, R.; Pomeisl, K.; Pomeislová, A.; Slavětínská, L. Poštová; Rubešová, P. 1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β. Bioorganic & Medicinal Chemistry 2021, 32 (February), nestránkováno.

Fadeev, A.; Makarov, A. S.; Uchuskin, M. G. Acid-Catalyzed Cascade Reaction of 2-Alkylfurans with α,β-Unsaturated Ketones: A Shortcut to 2,3,5-Trisubstituted Furans. Journal of Organic Chemistry 2021, 86 (23), 17362-17370.

Břehová, P.; Česnek, M.; Dračínský, M.; Chaloupecká, E.; Janeba, Z.; Mertlíková-Kaiserová, H.; Skácel, J.; Soto-Velasquez, M. P.; Tloušťová, E.; Watts, V. J. Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases. European Journal of Medicinal Chemistry 2021, 222 (October 15 2021), nestránkováno.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.