Publications

Machara, A.; Svoboda, J. Thiophenium-ylides: Synthesis and reactivity. Chemical Papers 2013, 67 (1) DOI: 10.2478/s11696-012-0222-7.

Machara, A.; D. Cox, P.; Hudlicky, T. ChemInform Abstract: Synthesis of Nalbuphine from Oripavine via N-Demethylation of N-Cyclobutylmethyl Oripavine. ChemInform 2012, 43 (19), no-no DOI: 10.1002/chin.201219209.

Machara, A.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Naltrexone by Palladium-Catalyzed N -Demethylation/Acylation of Oxymorphone: The Benefit of CH Activation and the Intramolecular Acyl Transfer from C-14 Hydroxy. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2713-2718 DOI: 10.1002/adsc.201200677.

Riedl, J.; Ménová, P.; Pohl, R.; Orság, P.; Fojta, M.; Hocek, M. GFP-like Fluorophores as DNA Labels for Studying DNA–Protein Interactions. The Journal of Organic Chemistry 2012, 77 (18), 8287-8293 DOI: 10.1021/jo301684b.

Machara, A.; Werner, L.; Endoma-Arias, M. Ann; D. Cox, P.; Hudlicky, T. Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium-Catalyzed N-Demethylation/Acylation and/or Concomitant O-Demethylation. Advanced Synthesis & Catalysis 2012, 354 (4), 613-626 DOI: 10.1002/adsc.201100807.

Ménová, P.; Hocek, M. Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction. Chemical Communications 2012, 48 (55), 6921 DOI: 10.1039/c2cc32930a.

Perlíková, P.; Martínez, N. Jornet; Slavětínská, L.; Hocek, M. Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines. Tetrahedron 2012, 68 (39), 8300-8310 DOI: 10.1016/j.tet.2012.07.033.

Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. Ann; Duchek, J.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Unexpected N -Demethylation of Oxymorphone and Oxycodone N -Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2706-2712 DOI: 10.1002/adsc.201200676.

Sun, C.; Bojdys, M. J.; Clarke, S. M.; Harper, L. D.; Jefferson, A.; Castro, M. A.; Medina, S. Bulk and Adsorbed Monolayer Phase Behavior of Binary Mixtures of Undecanoic Acid and Undecylamine: Catanionic Monolayers. Langmuir 2011, 27 (7), 3626-3637 DOI: 10.1021/la1048198.

Číhalová, S.; Valero, G.; Schimer, J.; Humpl, M.; Dračínský, M.; Moyano, A.; Rios, R.; Vesely, J. Highly enantioselective organocatalytic cascade reaction for the synthesis of piperidines and oxazolidines. Tetrahedron 2011, 67 (46), 8942-8950 DOI: 10.1016/j.tet.2011.08.079.

Malkov, A. V.; Kysilka, O.; Edgar, M.; Kadlcikova, A.; Kotora, M.; Kočovský, P. A Novel Bifunctional Allyldisilane as a Triple Allylation Reagent in the Stereoselective Synthesis of Trisubstituted Tetrahydrofurans. Chemistry - A European Journal 2011, 17 (26), 7162-7166 DOI: 10.1002/chem.201100513.

Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.; Andraos, J. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency Metrics. The Journal of Organic Chemistry 2011, 76 (24), 10050-10067 DOI: 10.1021/jo2018872.

Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.; Andraos, J. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency Metrics. The Journal of Organic Chemistry 2011, 76 (24), 10050-10067 DOI: 10.1021/jo2018872.

Tichotová, L.; Matoušová, E.; Špulák, M.; Kuneš, J.; Votruba, I.; Buchta, V.; Pour, M. Synthesis and biological activity of desmethoxy analogues of coruscanone A. Bioorganic & Medicinal Chemistry Letters 2011, 21 (20), 6062-6066 DOI: 10.1016/j.bmcl.2011.08.059.

Werner, L.; Machara, A.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Synthesis of Buprenorphine from Oripavine via N-Demethylation of Oripavine Quaternary Salts. The Journal of Organic Chemistry 2011, 76 (11), 4628-4634 DOI: 10.1021/jo200567n.

Matoušová, E.; Růžička, A.; Kuneš, J.; Králová, J.; Pour, M. TFP as a ligand in Au(i)-catalyzed dihydropyran synthesis. Unprecedented rearrangement of dihydropyrans into cyclopentenones. Chemical Communications 2011, 47 (33), 9390 DOI: 10.1039/c1cc13525b.

Kamlar, M.; Bravo, N.; Alba, A. - N. R.; Hybelbauerová, S.; Císařová, I.; Vesely, J.; Moyano, A.; Rios, R. Highly Enantioselective Addition of 1-Fluoro-1-nitro(phenylsulfonyl)methane to α,β-Unsaturated Aldehydes. European Journal of Organic Chemistry 2010, 2010 (28), 5464-5470 DOI: 10.1002/ejoc.201000851.

Werner, L.; Machara, A.; Hudlicky, T. Short Chemoenzymatic Azide-Free Synthesis of Oseltamivir (Tamiflu): Approaching the Potential for Process Efficiency. Advanced Synthesis & Catalysis 2010, 352 (1), 195-200 DOI: 10.1002/adsc.200900844.

Companyó, X.; Hejnová, M.; Kamlar, M.; Vesely, J.; Moyano, A.; Rios, R. Highly enantioselective fluoromalonate addition to α,β-unsaturated aldehydes. Tetrahedron Letters 2009, 50 (35), 5021-5024 DOI: 10.1016/j.tetlet.2009.06.092.

Valero, G.; Schimer, J.; Císařová, I.; Vesely, J.; Moyano, A.; Rios, R. Highly enantioselective organocatalytic synthesis of piperidines. Formal synthesis of (−)-Paroxetine. Tetrahedron Letters 2009, 50 (17), 1943-1946 DOI: 10.1016/j.tetlet.2009.02.049.

Machara, A.; Kozmík, V.; Pojarová, M.; Dvořáková, H.; Svoboda, J. Preparation and rearrangement study of novel thiophenium- and selenophenium-ylides. Collection of Czechoslovak Chemical Communications 2009, 1 DOI: 10.1135/cccc2009001.

Bojdys, M. J.; Müller, J. - O.; Antonietti, M.; Thomas, A. Ionothermal Synthesis of Crystalline, Condensed, Graphitic Carbon Nitride. Chemistry - A European Journal 2008, 14 (27), 8177-8182 DOI: 10.1002/chem.200800190.

Malkov, A. V.; Ramírez-López, P.; Bendová), L. Biedermann; Rulíšek, L.; Dufková, L.; Kotora, M.; Zhu, F.; Kočovský, P. On the mechanism of asymmetric allylation of aldehydes with allyltrichlorosi lanes catalyzed by QUINOX, a chiral lsoquinoline N-oxide. Journal of the American Chemical Society 2008, 130 (15), 5341-5348 DOI: 10.1021/ja711338q.

Malkov, A. V.; Westwater, M. - M.; Gutnov, A.; Ramírez-López, P.; Friscourt, F.; Kadlcikova, A.; Hodačová, J.; Rankovic, Z.; Kotora, M.; Kočovský, P. New pyridine N-oxides as chiral organocatalysts in the asymmetric allylation of aromatic aldehydes. Tetrahedron 2008, 64 (49), 11335-11348 DOI: 10.1016/j.tet.2008.08.084.

Machara, A.; Pojarová, M.; Svoboda, J. Synthesis and Cycloaddition Reaction of 3-Vinylthieno[3,2-b][1]benzothiophene. Collection of Czechoslovak Chemical Communications 2007, 72 (7), 952-964 DOI: 10.1135/cccc20070952.