Publications

Found 157 results
Author Title Type [ Year(Desc)]
Filters: First Letter Of Last Name is P  [Clear All Filters]
2012
Riedl, J.; Pohl, R.; Ernsting, N. P.; Orság, P.; Fojta, M.; Hocek, M. Labelling of nucleosides and oligonucleotides by solvatochromic 4-aminophthalimide fluorophore for studying DNA–protein interactions. Chemical Science 2012, 3 (9), 2797 DOI: 10.1039/c2sc20404e.
Prchalová, E.; Votruba, I.; Kotora, M. Sphingosine and clavaminol H derivatives bearing fluorinated chains and their cytotoxic activity. Journal of Fluorine Chemistry 2012, 141, 49-57 DOI: 10.1016/j.jfluchem.2012.06.005.
Nauš, P.; Perlíková, P.; Bourderioux, A.; Pohl, R.; Slavětínská, L.; Votruba, I.; Bahador, G.; Birkuš, G.; Cihlář, T.; Hocek, M. Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (17), 5202-5214 DOI: 10.1016/j.bmc.2012.07.003.
Nauš, P.; Perlíková, P.; Bourderioux, A.; Pohl, R.; Slavětínská, L.; Votruba, I.; Bahador, G.; Birkuš, G.; Cihlář, T.; Hocek, M. Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (17), 5202-5214 DOI: 10.1016/j.bmc.2012.07.003.
Tichý, M.; Pohl, R.; Xu, H. Ying; Chen, Y. - L.; Yokokawa, F.; Shi, P. - Y.; Hocek, M. Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (20), 6123-6133 DOI: 10.1016/j.bmc.2012.08.021.
Perlíková, P.; Martínez, N. Jornet; Slavětínská, L.; Hocek, M. Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines. Tetrahedron 2012, 68 (39), 8300-8310 DOI: 10.1016/j.tet.2012.07.033.
Popr, M.; Hybelbauerová, S.; Jindřich, J. Synthesis of 3I-O and 2I-O-monosubstituted derivatives of per-6-azido-β-cyclodextrin—potential molecular scaffolds. Carbohydrate Research 2012, 361, 148-154 DOI: 10.1016/j.carres.2012.09.003.
Chapuis, H.; Kubelka, T.; Joubert, N.; Pohl, R.; Hocek, M. Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2′-Deoxyribonucleosides. European Journal of Organic Chemistry 2012, 2012 (9), 1759-1767 DOI: 10.1002/ejoc.201101662.
Raindlová, V.; Pohl, R.; Hocek, M. Synthesis of Aldehyde-Linked Nucleotides and DNA and Their Bioconjugations with Lysine and Peptides through Reductive Amination. Chemistry - A European Journal 2012, 18 (13), 4080-4087 DOI: 10.1002/chem.201103270.
Raindlová, V.; Pohl, R.; Klepetářová, B.; Havran, L.; Šimková, E.; Horáková, P.; Pivonkova, H.; Fojta, M.; Hocek, M. Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling. ChemPlusChem 2012, 77 (8), 652-662 DOI: 10.1002/cplu.201200056.
Raindlová, V.; Pohl, R.; Klepetářová, B.; Havran, L.; Šimková, E.; Horáková, P.; Pivonkova, H.; Fojta, M.; Hocek, M. Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling. ChemPlusChem 2012, 77 (8), 652-662 DOI: 10.1002/cplu.201200056.
2013
Perlíková, P.; Konečný, P.; Nauš, P.; Snášel, J.; Votruba, I.; Džubák, P.; Pichová, I.; Hajdúch, M.; Hocek, M. 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents. MedChemComm 2013, 4 (11), 1497 DOI: 10.1039/c3md00232b.
Perlíková, P.; Konečný, P.; Nauš, P.; Snášel, J.; Votruba, I.; Džubák, P.; Pichová, I.; Hajdúch, M.; Hocek, M. 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents. MedChemComm 2013, 4 (11), 1497 DOI: 10.1039/c3md00232b.
Dadová, J.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Aqueous Heck Cross-Coupling Preparation of Acrylate-Modified Nucleotides and Nucleoside Triphosphates for Polymerase Synthesis of Acrylate-Labeled DNA. The Journal of Organic Chemistry 2013, 78 (19), 9627-9637 DOI: 10.1021/jo4011574.
Balintová, J.; Plucnara, M.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases. Chemistry - A European Journal 2013, 19 (38), 12720-12731 DOI: 10.1002/chem.201301868.
Balintová, J.; Plucnara, M.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases. Chemistry - A European Journal 2013, 19 (38), 12720-12731 DOI: 10.1002/chem.201301868.
Klečka, M.; Pohl, R.; Čejka, J.; Hocek, M. Direct C–H sulfenylation of purines and deazapurines. Organic & Biomolecular Chemistry 2013, 11 (31), 5189 DOI: 10.1039/c3ob40881g.
Fanfrlík, J.; Kolář, M.; Kamlar, M.; Hurný, D.; Ruiz, F. X.; Cousido-Siah, A.; Mitschler, A.; Řezáč, J.; Munusamy, E.; Lepšík, M.; et al. Modulation of Aldose Reductase Inhibition by Halogen Bond Tuning. ACS Chemical Biology 2013, 8 (11), 2484-2492 DOI: 10.1021/cb400526n.
Kamlar, M.; Putaj, P.; Vesely, J. Organocatalytic alkynylation of densely functionalized monofluorinated derivatives: C(sp3)–C(sp) coupling. Tetrahedron Letters 2013, 54 (16), 2097-2100 DOI: 10.1016/j.tetlet.2013.02.023.
Ménová, P.; Cahová, H.; Plucnara, M.; Havran, L.; Fojta, M.; Hocek, M. Polymerase synthesis of oligonucleotides containing a single chemically modified nucleobase for site-specific redox labelling. Chemical Communications 2013, 49 (41), 4652 DOI: 10.1039/c3cc41438h.
Tichý, M.; Pohl, R.; Tloušt’ová, E.; Weber, J.; Bahador, G.; Lee, Y. - J.; Hocek, M. Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2013, 21 (17), 5362-5372 DOI: 10.1016/j.bmc.2013.06.011.
Perlíková, P.; Eberlin, L.; Ménová, P.; Raindlová, V.; Slavětínská, L.; Tloušťová, E.; Bahador, G.; Lee, Y. - J.; Hocek, M. Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines. ChemMedChem 2013, 8 (5), 832-846 DOI: 10.1002/cmdc.201300047.
Kalachova, L.; Pohl, R.; Bednárová, L.; Fanfrlík, J.; Hocek, M. Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations. Org. Biomol. Chem. 2013, 11 (1), 78-89 DOI: 10.1039/C2OB26881G.
Dadová, J.; Orság, P.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M. Vinylsulfonamide and Acrylamide Modification of DNA for Cross-linking with Proteins. Angewandte Chemie International Edition 2013, 52 (40), 10515-10518 DOI: 10.1002/anie.201303577.
2014
Dziuba, D.; Pohl, R.; Hocek, M. Bodipy-Labeled Nucleoside Triphosphates for Polymerase Synthesis of Fluorescent DNA. Bioconjugate Chemistry 2014, 25 (11), 1984-1995 DOI: 10.1021/bc5003554.
xs sm md lg