Publications

Janková, Š.; Schulz, J.; Hybelbauerová, S.; Císařová, I.; Štěpnička, P.; Kotora, M. Synthesis of 1,2,3,4-Tetramethyl- and 1,2,3,4-Tetraethylfluorene through a Dewar Benzene Pathway: Synthesis of 1,2,3,4-Tetramethyl- and 1,2,3,4-Tetraethylfluorene. European Journal of Organic Chemistry 2013, 2013 (1), 44-47 DOI: 10.1002/ejoc.201201343.

Kubelka, T.; Slavětínská, L.; Eigner, V.; Hocek, M. Synthesis of 2,6-disubstituted pyridin-3-yl C-2′-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides. Organic & Biomolecular Chemistry 2013, 11 (28), 4702 DOI: 10.1039/c3ob40774h.

Machara, A.; Svoboda, J. Thiophenium-ylides: Synthesis and reactivity. Chemical Papers 2013, 67 (1) DOI: 10.2478/s11696-012-0222-7.

Kubelka, T.; Slavětínská, L.; Hocek, M. A General Regioselective Approach to 2,4-Disubstituted Pyrimidin-5-yl C-2-Deoxyribonucleosides. Synthesis 2012, 44 (06), 953-965 DOI: 10.1055/s-0031-1289694.

Řezanka, M.; Řezanka, P.; Sýkora, D.; Jindřich, J.; Král, V. Impact of substituent position in monosubstituted α-cyclodextrins on enantioselectivity in capillary electrophoresis. Journal of Separation Science 2012, 35 (7), 811–815 DOI: 10.1002/jssc.201101034.

Bojdys, M. J.; Hasell, T.; Severin, N.; Jelfs, K. E.; Rabe, J. P.; Cooper, A. I. Porous organic cage crystals: characterising the porous crystal surface. Chemical Communications 2012, 48 (98), 11948 DOI: 10.1039/c2cc36602a.

Schimer, J.; Cígler, P.; Vesely, J.; Šašková, K. Grantz; Lepšík, M.; Brynda, J.; Řezáčová, P.; Kožíšek, M.; Císařová, I.; Oberwinkler, H.; et al. Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold. Journal of Medicinal Chemistry 2012, 55 (22), 10130-10135 DOI: 10.1021/jm301249q.

Schimer, J.; Cígler, P.; Vesely, J.; Šašková, K. Grantz; Lepšík, M.; Brynda, J.; Řezáčová, P.; Kožíšek, M.; Císařová, I.; Oberwinkler, H.; et al. Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold. Journal of Medicinal Chemistry 2012, 55 (22), 10130-10135 DOI: 10.1021/jm301249q.

Nauš, P.; Perlíková, P.; Bourderioux, A.; Pohl, R.; Slavětínská, L.; Votruba, I.; Bahador, G.; Birkuš, G.; Cihlář, T.; Hocek, M. Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (17), 5202-5214 DOI: 10.1016/j.bmc.2012.07.003.

Tichý, M.; Pohl, R.; Xu, H. Ying; Chen, Y. - L.; Yokokawa, F.; Shi, P. - Y.; Hocek, M. Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (20), 6123-6133 DOI: 10.1016/j.bmc.2012.08.021.

Perlíková, P.; Martínez, N. Jornet; Slavětínská, L.; Hocek, M. Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines. Tetrahedron 2012, 68 (39), 8300-8310 DOI: 10.1016/j.tet.2012.07.033.

Hessler, F.; Císařová, I.; Sedlák, D.; Bartůněk, P.; Kotora, M. Synthesis of Ferrocenestrone: the First Metallocene Based Steroid Analogue. Chemistry - A European Journal 2012, 18 (18), 5515-5518 DOI: 10.1002/chem.201200687.

Raindlová, V.; Pohl, R.; Klepetářová, B.; Havran, L.; Šimková, E.; Horáková, P.; Pivonkova, H.; Fojta, M.; Hocek, M. Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling. ChemPlusChem 2012, 77 (8), 652-662 DOI: 10.1002/cplu.201200056.

Kubelka, T.; Slavětínská, L.; Hocek, M. Synthesis of Substituted Benzyl Homo-C-Ribonucleosides and -Nucleotides as Carba Analogues of Phosphoribosylanthranilate. European Journal of Organic Chemistry 2012, 2012 (26), 4969-4981 DOI: 10.1002/ejoc.201200819.

Sun, C.; Bojdys, M. J.; Clarke, S. M.; Harper, L. D.; Jefferson, A.; Castro, M. A.; Medina, S. Bulk and Adsorbed Monolayer Phase Behavior of Binary Mixtures of Undecanoic Acid and Undecylamine: Catanionic Monolayers. Langmuir 2011, 27 (7), 3626-3637 DOI: 10.1021/la1048198.

Číhalová, S.; Valero, G.; Schimer, J.; Humpl, M.; Dračínský, M.; Moyano, A.; Rios, R.; Vesely, J. Highly enantioselective organocatalytic cascade reaction for the synthesis of piperidines and oxazolidines. Tetrahedron 2011, 67 (46), 8942-8950 DOI: 10.1016/j.tet.2011.08.079.

Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.; Andraos, J. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency Metrics. The Journal of Organic Chemistry 2011, 76 (24), 10050-10067 DOI: 10.1021/jo2018872.

Bojdys, M. J.; Briggs, M. E.; Jones, J. T. A.; Adams, D. J.; Chong, S. Y.; Schmidtmann, M.; Cooper, A. I. Supramolecular Engineering of Intrinsic and Extrinsic Porosity in Covalent Organic Cages. Journal of the American Chemical Society 2011, 133 (41), 16566-16571 DOI: 10.1021/ja2056374.

Tichotová, L.; Matoušová, E.; Špulák, M.; Kuneš, J.; Votruba, I.; Buchta, V.; Pour, M. Synthesis and biological activity of desmethoxy analogues of coruscanone A. Bioorganic & Medicinal Chemistry Letters 2011, 21 (20), 6062-6066 DOI: 10.1016/j.bmcl.2011.08.059.

Šnajdr, I.; Janoušek, Z.; Jindřich, J.; Kotora, M. Cross-metathesis of allylcarboranes with O-allylcyclodextrins. Beilstein Journal of Organic Chemistry 2010, 6, 1099-1105 DOI: 10.3762/bjoc.6.126.

Eignerová, B.; Sedlák, D.; Dračínský, M.; Bartůněk, P.; Kotora, M. Synthesis and Biochemical Characterization of a Series of 17α-Perfluoroalkylated Estradiols as Selective Ligands for Estrogen Receptor α. Journal of Medicinal Chemistry 2010, 53 (19), 6947-6953 DOI: 10.1021/jm100563h.

Sedlák, D.; Novák, P.; Kotora, M.; Bartůněk, P. Synthesis and Evaluation of 17α-Arylestradiols as Ligands for Estrogen Receptor α and β. Journal of Medicinal Chemistry 2010, 53 (10), 4290-4294 DOI: 10.1021/jm901898a.

Valero, G.; Schimer, J.; Císařová, I.; Vesely, J.; Moyano, A.; Rios, R. Highly enantioselective organocatalytic synthesis of piperidines. Formal synthesis of (−)-Paroxetine. Tetrahedron Letters 2009, 50 (17), 1943-1946 DOI: 10.1016/j.tetlet.2009.02.049.

Machara, A.; Kozmík, V.; Pojarová, M.; Dvořáková, H.; Svoboda, J. Preparation and rearrangement study of novel thiophenium- and selenophenium-ylides. Collection of Czechoslovak Chemical Communications 2009, 1 DOI: 10.1135/cccc2009001.

Janková, Š.; Císařová, I.; Uhlík, F.; Štěpnička, P.; Kotora, M. Synthesis and characterisation of Dewar benzene–ferrocene conjugates. Dalton Transactions 2009, No. 17, 3137 DOI: 10.1039/b904488b.