Publications
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorganic and Medicinal Chemistry Letters 2022, 76 (November), nestránkováno.
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases. European Journal of Medicinal Chemistry 2023, 260 (November).
Hydrogen-Bonding Interactions of 8-Substituted Purine Derivatives. ACS Omega 2023, 8 (28), 25538-25548.
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors. ACS Omega 2023, 8 (30), 27410-27418.
Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors. Bioorganic and Medicinal Chemistry Letters 2024, 97 (1 January 2024).
Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides. RSC Medicinal Chemistry 2024, nestránkováno.