Publications

Misehe, M.; Šála, M.; Matoušová, M.; Hercík, K.; Kocek, H.; Chalupská, D.; Chaloupecká, E.; Hájek, M.; Bouřa, E.; Mertlíková-Kaiserová, H.; et al. Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors. Bioorganic and Medicinal Chemistry Letters 2024, 97 (1 January 2024).

Kocek, H.; Chalupská, D.; Dejmek, M.; Dvořáková, A.; Zgarbová, M.; Šála, M.; Chalupský, K.; Krafčíková, P.; Otava, T.; Drexler, M.; et al. Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides. RSC Medicinal Chemistry 2024, nestránkováno.

Prener, L.; Baszczyňski, O.; Kaiser, M. Maxmilian; Dračínský, M.; Stepan, G.; Lee, Y. - J.; Brumshtein, B.; Yu, H.; Jansa, P.; Lansdon, E. B.; et al. Design and Synthesis of Novel HIV-1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties. Journal of Medicinal Chemistry 2023, 66 (3), 1761-1777.

Skácel, J.; Djukic, S.; Baszczyňski, O.; Kalčic, F.; Bílek, T.; Chalupský, K.; Kozák, J.; Dvořáková, A.; Tloušťová, E.; Kráľová, Z.; et al. Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors. Journal of Medicinal Chemistry 2023, 66 (10), 6652-6681.

Novotná, K.; Tenora, L.; Prchalová, E.; Paule, J.; Alt, J.; Veeravalli, V.; Lam, J.; Wu, Y.; Šnajdr, I.; Gori, S.; et al. Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery. Journal of Medicinal Chemistry 2023, 66 (22), 15493-15510.

Čihák, M.; Hurný, D.; Malečková, A.; Štuka, Č.; Tonar, Z.; Vejražka, M. "Desatero" akademického pedagoga. https://karlovkaonline.cz/wp-content/uploads/2021/04/UK_fond-desatero_www.pdf, 2021.

Bělinová, T.; Beneš, H.; Groborz, O.; Heizer, T.; Herynek, V.; Hrubý, M.; Loukotová, L.; Raabová, H.; Švec, P. Direct Comparison of Analogous Amphiphilic Gradient and Block Polyoxazolines. Macromolecules 2021, 54 (17), 8182-8194.

Baszczyňski, O.; Dračínský, M.; Dvořáková, A.; Hodek, J.; Chalupský, K.; Janeba, Z.; Kalčic, F.; Kaiserová, H. Mertlíkov; Strmeň, T.; Šebestík, J.; et al. Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties. Journal of Medicinal Chemistry 2021, 64 (22), 16425-16449.

Kasireddy, S. Reddy; Míšek, J.; Nosek, V.; Tarallo, V. Development of a simple high-throughput assay for directed evolution of enantioselective sulfoxide reductases. Chemical Communications 2020, 56 (40), 5386-5388 DOI: 10.1039/d0cc01660h.

Docekal, V.; Šimek, M.; Dračínský, M.; Vesely, J. Decarboxylative Organocatalytic Allylic Amination of Morita-Baylis-Hillman Carbamates. Chemistry-a European Journal 2018, 24 (51), 13441-13445 DOI: 10.1002/chem.201803677.

Andris, E.; Navrátil, R.; Jašík, J.; Sabenya, G.; Costas, M.; Srnec, M.; Roithová, J. Detection of Indistinct Fe-N Stretching Bands in Iron(V) Nitrides by Photodissociation Spectroscopy. Chemistry-a European Journal 2018, 24 (20), 5078-5081 DOI: 10.1002/chem.201705307.

Makukhin, N.; Nosek, V.; Míšek, J. Development of a Ratiometric Fluorescent Probe with Two Reactive Sulfoxides for Monitoring the Activity of Methionine Sulfoxide Reductase A. Synthesis-Stuttgart 2018, 50 (4), 772-777 DOI: 10.1055/s-0036-1591888.

Kaiser, R. P.; Ulc, J.; Císařová, I.; Necas, D. Direct regioselective C-H borylation of [5]helicene. Rsc Advances 2018, 8 (1), 580-583 DOI: 10.1039/c7ra13021j.

Baumgartner, B.; Bojdys, M. J.; Skrinjar, P.; Unterlass, M. M. Design Strategies in Hydrothermal Polymerization of Polyimides. Macromolecular Chemistry and Physics 2016, 217 (3), 485-500 DOI: 10.1002/macp.201500287.

Machara, A.; Endoma-Arias, M. Ann A.; Císařová, I.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Noroxymorph­one from Thebaine: Unusual Ce ^IV Oxidation of a Methoxydiene-Iron Complex to an Enone-γ-Nitrate. European Journal of Organic Chemistry 2016, 2016 (8), 1500-1503 DOI: 10.1002/ejoc.201600153.

Jelinek, I.; Jindřich, J.; Dian, J. The Development of Optical Sensor with Chemically Modified Electroluminescence Diodes. Chemicke Listy 2015, 109 (5), 377-384.

Banwell, M. G.; Buckler, J. N.; Jackson, C. J.; Lan, P.; Ma, X.; Matoušová, E.; Nugent, J. Devising New Syntheses of the Alkaloid Galanthamine, a Potent and Clinically Deployed Inhibitor of Acetylcholine Esterase; Elsevier, 2015; Vol. 11, pp 29-50.

A. Downey, M.; Richter, C.; Pohl, R.; Mahrwald, R.; Hocek, M. Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose. Organic Letters 2015, 17 (18), 4604-4607 DOI: 10.1021/acs.orglett.5b02332.

Sabat, N.; Klečka, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M. Direct C-H amination and C-H chloroamination of 7-deazapurines. RSC Adv. 2014 DOI: 10.1039/C4RA13143F.

Klečka, M.; Pohl, R.; Čejka, J.; Hocek, M. Direct C–H sulfenylation of purines and deazapurines. Organic & Biomolecular Chemistry 2013, 11 (31), 5189 DOI: 10.1039/c3ob40881g.

Machara, A.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Naltrexone by Palladium-Catalyzed N -Demethylation/Acylation of Oxymorphone: The Benefit of CH Activation and the Intramolecular Acyl Transfer from C-14 Hydroxy. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2713-2718 DOI: 10.1002/adsc.201200677.

Holec, T.; Chvojka, T.; Jelinek, I.; Jindrich, J.; Nemec, I.; Pelant, I.; Valenta, J.; Dian, J. Determination of sensoric parameters of porous silicon in sensing of organic vapors. Materials Science and Engineering: C 2002, 19 (1-2), 251-254 DOI: 10.1016/S0928-4931(01)00394-0.

Pumera, M.; Jelinek, I.; Jindrich, J. Determination of cyclodextrins and their derivatives by capillary electrophoresis with indirect UV and conductivity detection. Fresenius Journal of Analytical Chemistry 2001, 369 (7-8), 666-669 DOI: 10.1007/s002160100721.

Pumera, M.; Jelı́nek, I.; Jindřich, J.; Coufal, P.; Horský, J. Determination of cyclodextrin content using periodate oxidation by capillary electrophoresis. Journal of Chromatography A 2000, 891 (1), 201-206 DOI: 10.1016/S0021-9673(00)00628-2.

Balzarini, J.; Holy, A.; Jindrich, J.; Naesens, L.; Snoeck, R.; Schols, D.; De Clercq, E. Differential Antiherpesvirus and Antiretrovirus Effects of the (S) and (R) Enantiomers of Acyclic Nucleoside Phosphonates - Potent and Selective Invitro and Invivo Antiretrovirus Activities of (R)-9-(2-Phosphonomethoxypropyl)-2,6-Diaminopurine. Antimicrobial Agents and Chemotherapy 1993, 37 (2), 332-338 DOI: 10.1128/AAC.37.2.332.