Publications

Holy, A.; Dvorakova, H.; Jindrich, J.; Masojidkova, M.; Budesinsky, M.; Balzarini, J.; Andrei, G.; DeClercq, E. Acyclic Nucleotide Analogs Derived from 8-Azapurines:  Synthesis and Antiviral Activity. Journal of Medicinal Chemistry 1996, 39 (20), 4073-4088 DOI: 10.1021/jm960314q.

Slavíčková, M.; Pohl, R.; Hocek, M. Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2′-Deoxyadenosine, dATP and DNA. The Journal of Organic Chemistry 2016, 81 (22), 11115-11125 DOI: 10.1021/acs.joc.6b02098.

Šnajdr, I.; Janoušek, Z.; Takagaki, M.; Císařová, I.; Hosmane, N. S.; Kotora, M. Alpha (α-) and beta (β-carboranyl-C-deoxyribosides: Syntheses, structures and biological evaluation. European Journal of Medicinal Chemistry 2014, 83, 389-397 DOI: 10.1016/j.ejmech.2014.06.005.

Císařová, I.; Holovko-Kamoshenkova, O. M.; Hrdina, R.; Koucký, F.; Machalický, O. Annulated carbamates are precursors for the ring contraction of the adamantane framework. RSC Advances [online] 2022, 12 (48), 31056-31060.

Císařová, I.; Holovko-Kamoshenkova, O. M.; Hrdina, R.; Koucký, F.; Machalický, O. Annulated carbamates are precursors for the ring contraction of the adamantane framework. RSC Advances [online] 2022, 12 (48), 31056-31060.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.

Dadová, J.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Aqueous Heck Cross-Coupling Preparation of Acrylate-Modified Nucleotides and Nucleoside Triphosphates for Polymerase Synthesis of Acrylate-Labeled DNA. The Journal of Organic Chemistry 2013, 78 (19), 9627-9637 DOI: 10.1021/jo4011574.

Dadová, J.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Aqueous Heck Cross-Coupling Preparation of Acrylate-Modified Nucleotides and Nucleoside Triphosphates for Polymerase Synthesis of Acrylate-Labeled DNA. The Journal of Organic Chemistry 2013, 78 (19), 9627-9637 DOI: 10.1021/jo4011574.

Kamlar, M.; Císařová, I.; Hybelbauerová, S.; Vesely, J. Asymmetric Allylic Amination of Morita-Baylis-Hillman Carbonates with Silylated tert-Butylhydroxycarbamate Derivatives. European Journal of Organic Chemistry 2017, No. 14, 1926-1930 DOI: 10.1002/ejoc.201700222.

Balintová, J.; Špaček, J.; Pohl, R.; Brázdová, M.; Havran, L.; Fojta, M.; Hocek, M. Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions. Chem. Sci. 2015, 6 (1), 575-587 DOI: 10.1039/C4SC01906G.

Balintová, J.; Špaček, J.; Pohl, R.; Brázdová, M.; Havran, L.; Fojta, M.; Hocek, M. Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions. Chem. Sci. 2015, 6 (1), 575-587 DOI: 10.1039/C4SC01906G.

Dadová, J.; Vrábel, M.; Adámik, M.; Brázdová, M.; Pohl, R.; Fojta, M.; Hocek, M. Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking. Chemistry - A European Journal 2015, 21 (45), 16091-16102 DOI: 10.1002/chem.201502209.

Balintová, J.; Plucnara, M.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases. Chemistry - A European Journal 2013, 19 (38), 12720-12731 DOI: 10.1002/chem.201301868.

Balintová, J.; Plucnara, M.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases. Chemistry - A European Journal 2013, 19 (38), 12720-12731 DOI: 10.1002/chem.201301868.

Brynda, J.; Fanfrlík, J.; Hadzima, M.; Hánová, I.; Horn, M.; Houštecká, R.; Lepšík, M.; Majer, P.; Mareš, M.; Mertlíková-Kaiserová, H.; et al. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of Medicinal Chemistry 2020, 63 (4), 1576-1596 DOI: 10.1021/acs.jmedchem.9b01351.

Brynda, J.; Fanfrlík, J.; Hadzima, M.; Hánová, I.; Horn, M.; Houštecká, R.; Lepšík, M.; Majer, P.; Mareš, M.; Mertlíková-Kaiserová, H.; et al. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of Medicinal Chemistry 2020, 63 (4), 1576-1596 DOI: 10.1021/acs.jmedchem.9b01351.

Brynda, J.; Fanfrlík, J.; Hadzima, M.; Hánová, I.; Horn, M.; Houštecká, R.; Lepšík, M.; Majer, P.; Mareš, M.; Mertlíková-Kaiserová, H.; et al. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of Medicinal Chemistry 2020, 63 (4), 1576-1596 DOI: 10.1021/acs.jmedchem.9b01351.

Brynda, J.; Fanfrlík, J.; Hadzima, M.; Hánová, I.; Horn, M.; Houštecká, R.; Lepšík, M.; Majer, P.; Mareš, M.; Mertlíková-Kaiserová, H.; et al. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of Medicinal Chemistry 2020, 63 (4), 1576-1596 DOI: 10.1021/acs.jmedchem.9b01351.

Dziuba, D.; Pohl, R.; Hocek, M. Bodipy-Labeled Nucleoside Triphosphates for Polymerase Synthesis of Fluorescent DNA. Bioconjugate Chemistry 2014, 25 (11), 1984-1995 DOI: 10.1021/bc5003554.

Güixens-Gallardo, P.; Zawada, Z.; Matyašovský, J.; Dziuba, D.; Pohl, R.; Kraus, T.; Hocek, M. Brightly Fluorescent 2 '-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in Cellulo Incorporation to DNA, Imaging, and Flow Cytometry. Bioconjugate Chemistry 2018, 29 (11), 3906-3912 DOI: 10.1021/acs.bioconjchem.8b00721.

Sun, C.; Bojdys, M. J.; Clarke, S. M.; Harper, L. D.; Jefferson, A.; Castro, M. A.; Medina, S. Bulk and Adsorbed Monolayer Phase Behavior of Binary Mixtures of Undecanoic Acid and Undecylamine: Catanionic Monolayers. Langmuir 2011, 27 (7), 3626-3637 DOI: 10.1021/la1048198.

Fojta, M.; Havran, L.; Hocek, M.; Kodr, D.; Lesnikowski, Z. J.; Ortiz, M.; O'Sullivan, C. Kathleen; Pohl, R.; Saftić, D. Pavlović; Simonova, A.; et al. Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing. Journal of the American Chemical Society 2021, 143 (18), 7124-7134.

Fojta, M.; Havran, L.; Hocek, M.; Kodr, D.; Lesnikowski, Z. J.; Ortiz, M.; O'Sullivan, C. Kathleen; Pohl, R.; Saftić, D. Pavlović; Simonova, A.; et al. Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing. Journal of the American Chemical Society 2021, 143 (18), 7124-7134.

Balintová, J.; Simonova, A.; Bialek-Pietras, M.; Olejniczak, A.; Lesnikowski, Z. J.; Hocek, M. Carborane-linked 2 '-deoxyuridine 5 '-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA. Bioorganic & Medicinal Chemistry Letters 2017, 27 (21), 4786-4788 DOI: 10.1016/j.bmcl.2017.09.064.