Publications

Machara, A.; D. Cox, P.; Hudlicky, T. ChemInform Abstract: Synthesis of Nalbuphine from Oripavine via N-Demethylation of N-Cyclobutylmethyl Oripavine. ChemInform 2012, 43 (19), no-no DOI: 10.1002/chin.201219209.

Machara, A.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Naltrexone by Palladium-Catalyzed N -Demethylation/Acylation of Oxymorphone: The Benefit of CH Activation and the Intramolecular Acyl Transfer from C-14 Hydroxy. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2713-2718 DOI: 10.1002/adsc.201200677.

Hartman, T.; Herzig, V.; Buděšínský, M.; Jindřich, J.; Cibulka, R.; Kraus, T. Flavin–cyclodextrin conjugates: effect of the structure on the catalytic activity in enantioselective sulfoxidations. Tetrahedron: Asymmetry 2012, 23 (22–23), 1571-1583 DOI: 10.1016/j.tetasy.2012.10.017.

Ćerňová, M.; Pohl, R.; Klepetářová, B.; Hocek, M. A General Regioselective Synthesis of 2,4-Diarylpyrimidines from 2- Thiouracil through Two Orthogonal Cross-Coupling Reactions. Synlett 2012, 23 (09), 1305-1308 DOI: 10.1055/s-0031-1290826.

Machara, A.; Werner, L.; Endoma-Arias, M. Ann; D. Cox, P.; Hudlicky, T. Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium-Catalyzed N-Demethylation/Acylation and/or Concomitant O-Demethylation. Advanced Synthesis & Catalysis 2012, 354 (4), 613-626 DOI: 10.1002/adsc.201100807.

Ren, S.; Bojdys, M. J.; Dawson, R.; Laybourn, A.; Khimyak, Y. Z.; Adams, D. J.; Cooper, A. I. Porous, Fluorescent, Covalent Triazine-Based Frameworks Via Room-Temperature and Microwave-Assisted Synthesis. Advanced Materials 2012, 24 (17), 2357-2361 DOI: 10.1002/adma.201200751.

Bojdys, M. J.; Hasell, T.; Severin, N.; Jelfs, K. E.; Rabe, J. P.; Cooper, A. I. Porous organic cage crystals: characterising the porous crystal surface. Chemical Communications 2012, 48 (98), 11948 DOI: 10.1039/c2cc36602a.

Schimer, J.; Cígler, P.; Vesely, J.; Šašková, K. Grantz; Lepšík, M.; Brynda, J.; Řezáčová, P.; Kožíšek, M.; Císařová, I.; Oberwinkler, H.; et al. Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold. Journal of Medicinal Chemistry 2012, 55 (22), 10130-10135 DOI: 10.1021/jm301249q.

Schimer, J.; Cígler, P.; Vesely, J.; Šašková, K. Grantz; Lepšík, M.; Brynda, J.; Řezáčová, P.; Kožíšek, M.; Císařová, I.; Oberwinkler, H.; et al. Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold. Journal of Medicinal Chemistry 2012, 55 (22), 10130-10135 DOI: 10.1021/jm301249q.

Nauš, P.; Perlíková, P.; Bourderioux, A.; Pohl, R.; Slavětínská, L.; Votruba, I.; Bahador, G.; Birkuš, G.; Cihlář, T.; Hocek, M. Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (17), 5202-5214 DOI: 10.1016/j.bmc.2012.07.003.

Tichý, M.; Pohl, R.; Xu, H. Ying; Chen, Y. - L.; Yokokawa, F.; Shi, P. - Y.; Hocek, M. Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (20), 6123-6133 DOI: 10.1016/j.bmc.2012.08.021.

Chapuis, H.; Kubelka, T.; Joubert, N.; Pohl, R.; Hocek, M. Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2′-Deoxyribonucleosides. European Journal of Organic Chemistry 2012, 2012 (9), 1759-1767 DOI: 10.1002/ejoc.201101662.

Korotvička, A.; Císařová, I.; Roithová, J.; Kotora, M. Synthesis of Aromatic Compounds by Catalytic C-C Bond Activation of Biphenylene or Angular [3]Phenylene. Chemistry - A European Journal 2012, 18 (14), 4200-4207 DOI: 10.1002/chem.201103888.

Hessler, F.; Císařová, I.; Sedlák, D.; Bartůněk, P.; Kotora, M. Synthesis of Ferrocenestrone: the First Metallocene Based Steroid Analogue. Chemistry - A European Journal 2012, 18 (18), 5515-5518 DOI: 10.1002/chem.201200687.

Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. Ann; Duchek, J.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Unexpected N -Demethylation of Oxymorphone and Oxycodone N -Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2706-2712 DOI: 10.1002/adsc.201200676.

Číhalová, S.; Dziedzic, P.; Córdova, A.; Vesely, J. Asymmetric Aza-Morita-Baylis-Hillman-Type Reactions: The Highly Enantioselective Reaction between Unmodified α,β- Unsaturated Aldehydes and N-Acylimines by Organo-co-catalysis. Advanced Synthesis & Catalysis 2011, 353 (7), 1096-1108 DOI: 10.1002/adsc.201000951.

Číhalová, S.; Dziedzic, P.; Córdova, A.; Vesely, J. Asymmetric Aza-Morita-Baylis-Hillman-Type Reactions: The Highly Enantioselective Reaction between Unmodified α,β- Unsaturated Aldehydes and N-Acylimines by Organo-co-catalysis. Advanced Synthesis & Catalysis 2011, 353 (7), 1096-1108 DOI: 10.1002/adsc.201000951.

Sun, C.; Bojdys, M. J.; Clarke, S. M.; Harper, L. D.; Jefferson, A.; Castro, M. A.; Medina, S. Bulk and Adsorbed Monolayer Phase Behavior of Binary Mixtures of Undecanoic Acid and Undecylamine: Catanionic Monolayers. Langmuir 2011, 27 (7), 3626-3637 DOI: 10.1021/la1048198.

Sun, C.; Bojdys, M. J.; Clarke, S. M.; Harper, L. D.; Jefferson, A.; Castro, M. A.; Medina, S. Bulk and Adsorbed Monolayer Phase Behavior of Binary Mixtures of Undecanoic Acid and Undecylamine: Catanionic Monolayers. Langmuir 2011, 27 (7), 3626-3637 DOI: 10.1021/la1048198.

Číhalová, S.; Valero, G.; Schimer, J.; Humpl, M.; Dračínský, M.; Moyano, A.; Rios, R.; Vesely, J. Highly enantioselective organocatalytic cascade reaction for the synthesis of piperidines and oxazolidines. Tetrahedron 2011, 67 (46), 8942-8950 DOI: 10.1016/j.tet.2011.08.079.

Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.; Andraos, J. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency Metrics. The Journal of Organic Chemistry 2011, 76 (24), 10050-10067 DOI: 10.1021/jo2018872.

Bojdys, M. J.; Briggs, M. E.; Jones, J. T. A.; Adams, D. J.; Chong, S. Y.; Schmidtmann, M.; Cooper, A. I. Supramolecular Engineering of Intrinsic and Extrinsic Porosity in Covalent Organic Cages. Journal of the American Chemical Society 2011, 133 (41), 16566-16571 DOI: 10.1021/ja2056374.

Bojdys, M. J.; Briggs, M. E.; Jones, J. T. A.; Adams, D. J.; Chong, S. Y.; Schmidtmann, M.; Cooper, A. I. Supramolecular Engineering of Intrinsic and Extrinsic Porosity in Covalent Organic Cages. Journal of the American Chemical Society 2011, 133 (41), 16566-16571 DOI: 10.1021/ja2056374.

Werner, L.; Machara, A.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Synthesis of Buprenorphine from Oripavine via N-Demethylation of Oripavine Quaternary Salts. The Journal of Organic Chemistry 2011, 76 (11), 4628-4634 DOI: 10.1021/jo200567n.

Kamlar, M.; Bravo, N.; Alba, A. - N. R.; Hybelbauerová, S.; Císařová, I.; Vesely, J.; Moyano, A.; Rios, R. Highly Enantioselective Addition of 1-Fluoro-1-nitro(phenylsulfonyl)methane to α,β-Unsaturated Aldehydes. European Journal of Organic Chemistry 2010, 2010 (28), 5464-5470 DOI: 10.1002/ejoc.201000851.