Publications

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Journal Article
Hessler, F.; Korotvička, A.; Nečas, D.; Valterová, I.; Kotora, M. Syntheses of a Flobufen Metabolite and Dapoxetine Based on Enantioselective Allylation of Aromatic Aldehydes: Syntheses of a Flobufen Metabolite and Dapoxetine. European Journal of Organic Chemistry 2014, 2014 (12), 2543-2548 DOI: 10.1002/ejoc.201301899.
Doleželová, E.; Downey, A. Michael; Hocek, M.; Nguyen, V. Hai; Pohl, R.; Rožánková, S.; Slapničková, M.; Tichý, M.; Tloušťová, E.; Zíková, A. Synthesis and anti-trypanosomal activity of 3'-fluororibonucleosides derived from 7-deazapurine nucleosides. Bioorganic and Medicinal Chemistry Letters 2021, 40 (May 15 2021), nestránkováno.
Doleželová, E.; Džubák, P.; Gurská, S.; Hajdúch, M.; Hocek, M.; Krajczyk, A.; Milisavljević, N.; Perlíková, P.; Slavětínská, L. Poštová; Slapničková, M.; et al. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS Infectious Diseases 2021, 7 (4), 917-926.
Doleželová, E.; Džubák, P.; Gurská, S.; Hajdúch, M.; Hocek, M.; Krajczyk, A.; Milisavljević, N.; Perlíková, P.; Slavětínská, L. Poštová; Slapničková, M.; et al. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS Infectious Diseases 2021, 7 (4), 917-926.
Tichý, M.; Pohl, R.; Xu, H. Ying; Chen, Y. - L.; Yokokawa, F.; Shi, P. - Y.; Hocek, M. Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (20), 6123-6133 DOI: 10.1016/j.bmc.2012.08.021.
Tichý, M.; Pohl, R.; Tloušt’ová, E.; Weber, J.; Bahador, G.; Lee, Y. - J.; Hocek, M. Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2013, 21 (17), 5362-5372 DOI: 10.1016/j.bmc.2013.06.011.
Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.
Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.
Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.
Bartova, K.; Džubák, P.; Fleuti, M. Heidi; Gurska, S.; Hajdúch, M.; Hocek, M.; Pavliš, P.; Slavětínská, L. Poštová; Tichý, M.; Tloušťová, E. Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides. Journal of Organic Chemistry 2020, 85 (16), 10539-10551 DOI: 10.1021/acs.joc.0c00928.
Bartova, K.; Džubák, P.; Fleuti, M. Heidi; Gurska, S.; Hajdúch, M.; Hocek, M.; Pavliš, P.; Slavětínská, L. Poštová; Tichý, M.; Tloušťová, E. Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides. Journal of Organic Chemistry 2020, 85 (16), 10539-10551 DOI: 10.1021/acs.joc.0c00928.
Klečka, M.; Slavětínská, L. Poštová; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides. Med. Chem. Commun. 2015, 6 (4), 576-580 DOI: 10.1039/C4MD00492B.
Klečka, M.; Slavětínská, L. Poštová; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides. Med. Chem. Commun. 2015, 6 (4), 576-580 DOI: 10.1039/C4MD00492B.
Perlíková, P.; Eberlin, L.; Ménová, P.; Raindlová, V.; Slavětínská, L.; Tloušťová, E.; Bahador, G.; Lee, Y. - J.; Hocek, M. Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines. ChemMedChem 2013, 8 (5), 832-846 DOI: 10.1002/cmdc.201300047.
Nauš, P.; Caletková, O.; Konečný, P.; Džubák, P.; Bogdanová, K.; Kolář, M.; Vrbková, J.; Slavětínská, L.; Tloušt’ová, E.; Perlíková, P.; et al. Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (3), 1097-1110 DOI: 10.1021/jm4018948.
Nauš, P.; Caletková, O.; Konečný, P.; Džubák, P.; Bogdanová, K.; Kolář, M.; Vrbková, J.; Slavětínská, L.; Tloušt’ová, E.; Perlíková, P.; et al. Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (3), 1097-1110 DOI: 10.1021/jm4018948.
Janková, Š.; Schulz, J.; Hybelbauerová, S.; Císařová, I.; Štěpnička, P.; Kotora, M. Synthesis of 1,2,3,4-Tetramethyl- and 1,2,3,4-Tetraethylfluorene through a Dewar Benzene Pathway: Synthesis of 1,2,3,4-Tetramethyl- and 1,2,3,4-Tetraethylfluorene. European Journal of Organic Chemistry 2013, 2013 (1), 44-47 DOI: 10.1002/ejoc.201201343.
Jindrich, J.; Harata, K.; Lindberg, B.; Pitha, J.; Seffers, P. Synthesis of 2(1),3(1)-O-(propane-1,2-diyl)- and 2(1),3(1)-O-(3-hydroxypropane-1,2-diyl)cyclomaltoheptaose. Carbohydrate Research 1997, 300 (4), 361-363.
Kubelka, T.; Slavětínská, L.; Eigner, V.; Hocek, M. Synthesis of 2,6-disubstituted pyridin-3-yl C-2′-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides. Organic & Biomolecular Chemistry 2013, 11 (28), 4702 DOI: 10.1039/c3ob40774h.
Perlíková, P.; Martínez, N. Jornet; Slavětínská, L.; Hocek, M. Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines. Tetrahedron 2012, 68 (39), 8300-8310 DOI: 10.1016/j.tet.2012.07.033.
Popr, M.; Hybelbauerová, S.; Jindřich, J. Synthesis of 3I-O and 2I-O-monosubstituted derivatives of per-6-azido-β-cyclodextrin—potential molecular scaffolds. Carbohydrate Research 2012, 361, 148-154 DOI: 10.1016/j.carres.2012.09.003.
Chapuis, H.; Kubelka, T.; Joubert, N.; Pohl, R.; Hocek, M. Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2′-Deoxyribonucleosides. European Journal of Organic Chemistry 2012, 2012 (9), 1759-1767 DOI: 10.1002/ejoc.201101662.
Raindlová, V.; Pohl, R.; Hocek, M. Synthesis of Aldehyde-Linked Nucleotides and DNA and Their Bioconjugations with Lysine and Peptides through Reductive Amination. Chemistry - A European Journal 2012, 18 (13), 4080-4087 DOI: 10.1002/chem.201103270.
Betík, R.; Herrmann, P.; Kotora, M. Synthesis of an (±)-Estrone Precursor: The Scope of Zr- and Co-Mediated Cycloannulations. European Journal of Organic Chemistry 2010, 2010 (4), 646-655 DOI: 10.1002/ejoc.200900937.
Hocek, M. Synthesis of Base-Modified 2′-Deoxyribonucleoside Triphosphates and Their Use in Enzymatic Synthesis of Modified DNA for Applications in Bioanalysis and Chemical Biology. The Journal of Organic Chemistry 2014, 79 (21), 9914-9921 DOI: 10.1021/jo5020799.
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