Publications

Benýšek, J.; Krečmerová, M.; Matoušová, M.; Kaiserová, H. Mertlíkov; Otmar, M.; Pohl, R.; Pomeisl, K.; Pomeislová, A.; Slavětínská, L. Poštová; Rubešová, P. 1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β. Bioorganic & Medicinal Chemistry 2021, 32 (February), nestránkováno.

Benýšek, J.; Krečmerová, M.; Matoušová, M.; Kaiserová, H. Mertlíkov; Otmar, M.; Pohl, R.; Pomeisl, K.; Pomeislová, A.; Slavětínská, L. Poštová; Rubešová, P. 1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β. Bioorganic & Medicinal Chemistry 2021, 32 (February), nestránkováno.

Kotora, M.; Hocek, M.; Turek, P.; Pohl, R.; Klepetářová, B.; Votruba, I.; Opekar, S. [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with α,ω-Diynes. HETEROCYCLES 2010, 82 (1), 895 DOI: 10.3987/COM-10-S(E)56.

Kotora, M.; Hocek, M.; Turek, P.; Pohl, R.; Klepetářová, B.; Votruba, I.; Opekar, S. [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with α,ω-Diynes. HETEROCYCLES 2010, 82 (1), 895 DOI: 10.3987/COM-10-S(E)56.

Kaiser, R. P.; Hessler, F.; Mosinger, J.; Císařová, I.; Kotora, M. A [2+2+2]-Cyclotrimerization Approach to Selectively Substituted Fluorenes and Fluorenols, and Their Conversion to 9,9′-Spirobifluorenes. Chemistry - A European Journal 2015, 21 (39), 13577-13582 DOI: 10.1002/chem.201502370.

Kaiser, R. P.; Hessler, F.; Mosinger, J.; Císařová, I.; Kotora, M. A [2+2+2]-Cyclotrimerization Approach to Selectively Substituted Fluorenes and Fluorenols, and Their Conversion to 9,9′-Spirobifluorenes. Chemistry - A European Journal 2015, 21 (39), 13577-13582 DOI: 10.1002/chem.201502370.

Matoušová, E.; Gyepes, R.; Císařová, I.; Kotora, M. [2+2+2]-Cyclotrimerization of 1-Cyclopropyl-1,6-diynes with Alkynes: Formation of Cyclopropylarenes. Advanced Synthesis & Catalysis 2016, 358 (2), 254-267 DOI: 10.1002/adsc.201500851.

Brunderová, M.; Hocek, M.; Ivancova, I.; Krömer, M.; Slavětínská, L. Poštová. 2-Formyl-dATP as Substrate for Polymerase Synthesis of Reactive DNA Bearing an Aldehyde Group in the Minor Groove. ChemPlusChem 2020, 85 (6), 1164-1170 DOI: 10.1002/cplu.202000287.

Drastík, M.; Holas, O.; Hroch, M.; Hutníková, M.; Kašpar, M.; Kudová, E.; Mičuda, S.; Pandey, A. V.; Pávek, P.; Smutný, T.; et al. 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism. Journal of Steroid Biochemistry and Molecular Biology 2020, 202 (September), nestránkováno DOI: 10.1016/j.jsbmb.2020.105702.

Drastík, M.; Holas, O.; Hroch, M.; Hutníková, M.; Kašpar, M.; Kudová, E.; Mičuda, S.; Pandey, A. V.; Pávek, P.; Smutný, T.; et al. 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism. Journal of Steroid Biochemistry and Molecular Biology 2020, 202 (September), nestránkováno DOI: 10.1016/j.jsbmb.2020.105702.

Janoušková, M.; Vaníková, Z.; Nici, F.; Boháčová, S.; Vitovska, D.; Šanderová, H.; Hocek, M.; Krásný, L. 5-(Hydroxymethyl) uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chemical Communications 2017, 53 (99), 13253-13255 DOI: 10.1039/c7cc08053k.

Cahová, H.; Panattoni, A.; Kielkowski, P.; Fanfrlík, J.; Hocek, M. 5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs. ACS Chemical Biology 2016, 11 (11), 3165-3171 DOI: 10.1021/acschembio.6b00714.

Perlíková, P.; Konečný, P.; Nauš, P.; Snášel, J.; Votruba, I.; Džubák, P.; Pichová, I.; Hajdúch, M.; Hocek, M. 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents. MedChemComm 2013, 4 (11), 1497 DOI: 10.1039/c3md00232b.

Kielkowski, P.; Fanfrlík, J.; Hocek, M. 7-Aryl-7-deazaadenine 2′-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations. Angewandte Chemie International Edition 2014, 53 (29), 7552-7555 DOI: 10.1002/anie.201404742.

Kamlar, M.; Císařová, I.; Veselý, J. Alkynylation of heterocyclic compounds using hypervalent iodine reagent. Org. Biomol. Chem. 2015, 13 (10), 2884-2889 DOI: 10.1039/C4OB02625J.

Šnajdr, I.; Janoušek, Z.; Takagaki, M.; Císařová, I.; Hosmane, N. S.; Kotora, M. Alpha (α-) and beta (β-carboranyl-C-deoxyribosides: Syntheses, structures and biological evaluation. European Journal of Medicinal Chemistry 2014, 83, 389-397 DOI: 10.1016/j.ejmech.2014.06.005.

Císařová, I.; Holovko-Kamoshenkova, O. M.; Hrdina, R.; Koucký, F.; Machalický, O. Annulated carbamates are precursors for the ring contraction of the adamantane framework. RSC Advances [online] 2022, 12 (48), 31056-31060.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.

Bednářová, E.; Kotora, M.; Malatinec, Š. Applications of Bolm's Ligand in Enantioselective Synthesis. Molecules 2020, 25 (4), nestránkováno DOI: 10.3390/molecules25050958.

Kamlar, M.; Císařová, I.; Hybelbauerová, S.; Vesely, J. Asymmetric Allylic Amination of Morita-Baylis-Hillman Carbonates with Silylated tert-Butylhydroxycarbamate Derivatives. European Journal of Organic Chemistry 2017, No. 14, 1926-1930 DOI: 10.1002/ejoc.201700222.

Topolovčan, N.; Panov, I.; Kotora, M. Bisallylation of Zirconacyclopentenes and Ring-Closing Metathesis: A Route to Eight-Membered-Ring Compounds. Synlett 2016, 27 (03), 432-436 DOI: 10.1055/s-0035-1560587.

Güixens-Gallardo, P.; Zawada, Z.; Matyašovský, J.; Dziuba, D.; Pohl, R.; Kraus, T.; Hocek, M. Brightly Fluorescent 2 '-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in Cellulo Incorporation to DNA, Imaging, and Flow Cytometry. Bioconjugate Chemistry 2018, 29 (11), 3906-3912 DOI: 10.1021/acs.bioconjchem.8b00721.

Fojta, M.; Havran, L.; Hocek, M.; Kodr, D.; Lesnikowski, Z. J.; Ortiz, M.; O'Sullivan, C. Kathleen; Pohl, R.; Saftić, D. Pavlović; Simonova, A.; et al. Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing. Journal of the American Chemical Society 2021, 143 (18), 7124-7134.

Herrmann, P.; Kotora, M. A catalytic and stoichiometric approach to the synthesis of the steroid B-ring en route to estratrienes. Tetrahedron Letters 2007, 48 (18), 3209-3212 DOI: 10.1016/j.tetlet.2007.03.018.