Publications

Dian, J.; Fourmentin, S.; Jindřich, J.; Palágyi, A. Cyclodextrin-based Schiff base pro-fragrances: Synthesis and release studies. Beilstein Journal of Organic Chemistry 2022, 18 (September), 1346-1354.

Císařová, I.; David, T.; Dračínský, M.; Jirák, D.; Jurok, R.; Kretschmer, J.; Kuchař, M.; Polášek, M.; Socha, O.; Vít, M. Paramagnetic encoding of molecules. Nature Communications [online] 2022, 13 (1), nestránkováno.

Baszczyňski, O.; Černý, J.; Čmoková, A.; Grobárová, V.; Kolařík, M.; Procházková, E.; Slapničková, M.; Štěpánek, O.; Zíková, A. Piperazine-Modified Ketoconazole Derivatives Show Increased Activity against Fungal and Trypanosomatid Pathogens. ChemMedChem 2022, 17 (21), nestránkováno.

Benýšek, J.; Krečmerová, M.; Matoušová, M.; Kaiserová, H. Mertlíkov; Otmar, M.; Pohl, R.; Pomeisl, K.; Pomeislová, A.; Slavětínská, L. Poštová; Rubešová, P. 1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β. Bioorganic & Medicinal Chemistry 2021, 32 (February), nestránkováno.

Benýšek, J.; Krečmerová, M.; Matoušová, M.; Kaiserová, H. Mertlíkov; Otmar, M.; Pohl, R.; Pomeisl, K.; Pomeislová, A.; Slavětínská, L. Poštová; Rubešová, P. 1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β. Bioorganic & Medicinal Chemistry 2021, 32 (February), nestránkováno.

Benýšek, J.; Krečmerová, M.; Matoušová, M.; Kaiserová, H. Mertlíkov; Otmar, M.; Pohl, R.; Pomeisl, K.; Pomeislová, A.; Slavětínská, L. Poštová; Rubešová, P. 1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β. Bioorganic & Medicinal Chemistry 2021, 32 (February), nestránkováno.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.

Bricout, H.; Caronia, E.; Galia, A.; Tichá, I. Chena; Jindřich, J.; Léger, B.; Menuel, S.; Monflier, É.; Noël, S.; Ponchel, A.; et al. Asymmetric hydrogenation of ethyl pyruvate over aqueous dispersed Pt nanoparticles stabilized by a cinchonidine-functionalized β-cyclodextrin. Catalysis Communications 2021, 150 (February), nestránkováno.

Fojta, M.; Havran, L.; Hocek, M.; Kodr, D.; Lesnikowski, Z. J.; Ortiz, M.; O'Sullivan, C. Kathleen; Pohl, R.; Saftić, D. Pavlović; Simonova, A.; et al. Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing. Journal of the American Chemical Society 2021, 143 (18), 7124-7134.

Groborz, O.; Holubová, M.; Hromádková, J.; Hrubý, M.; Lobaz, V.; Loukotová, L.; Pechrová, Z.; Rabyk, M.; Štěpánek, P.; Trhlíková, O. Chemically modified glycogens: How they influence formation of amyloid fibrils?. Soft Matter 2021, 17 (6), 1614-1627.

Dračínský, M.; Drastík, M.; Kašpar, M.; Klepetářová, B.; Kronenberger, T.; Kudová, E.; Mičuda, S.; Pávek, P.; Štefela, A. (E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells. Frontiers in Pharmacology 2021, 12 (August), nestránkováno.

Baszczyňski, O.; Císařová, I.; Flieger, M.; Kolařík, M.; Kucherak, O.; Procházková, E.; Stodůlková, E.; Tošner, Z. NMR Structure Elucidation of Naphthoquinones from Quambalaria cyanescens. Journal of Natural Products 2021, 84 (1), 46-55.

Gallardo, P. Güixens; Hocek, M.; Kraus, T.; Kuba, M.; Matyašovský, J.; Palágyi, A.; Pohl, R.; Tack, L. Nucleotides bearing aminophenyl- or aminonaphthyl-3-methoxychromone solvatochromic fluorophores for the enzymatic construction of DNA probes for the detection of protein-DNA binding. Organic and Biomolecular Chemistry 2021, 19 (45), 9966-9974.

Gallardo, P. Güixens; Hocek, M.; Kraus, T.; Kuba, M.; Matyašovský, J.; Palágyi, A.; Pohl, R.; Tack, L. Nucleotides bearing aminophenyl- or aminonaphthyl-3-methoxychromone solvatochromic fluorophores for the enzymatic construction of DNA probes for the detection of protein-DNA binding. Organic and Biomolecular Chemistry 2021, 19 (45), 9966-9974.

Baszczyňski, O.; Cigáň, M.; Filo, J.; Májek, M.; Procházková, E.; Straka, M.; Šimon, P. Phosphate linkers with traceable cyclic intermediates for self-immolation detection and monitoring. Chemical Communications 2021, 57 (2), 211-214.

Baszczyňski, O.; Gallardo, M. García; Procházková, E.; Šimon, P.; Tichotová, M. Phosphate-Based Self-Immolative Linkers for Tuneable Double Cargo Release. Chemistry - A European Journal 2021, 27 (50), 12763-12775.

Kočovský, P.; Kuneš, J.; Kysilka, O.; Májek, M.; Maříková, J.; Matouš, P.; Pour, M.; Růžička, A. Reaction Outcome Critically Dependent on the Method of Workup: An Example from the Synthesis of 1-Isoquinolones. Journal of Organic Chemistry 2021, 86 (12), 8078-8088.

Beier, P.; Janecký, L.; Klepetářová, B.; Markos, A.; Pohl, R. Stereoselective synthesis of (Z)-β-enamido fluorides from N-fluoroalkyl- and N-sulfonyl-1,2,3-triazoles. Organic Letters 2021, 23 (11), 4224-4227.

Hejdánek, J.; Hodek, J.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Pachl, P.; Radilová, K.; Řezáčová, P.; Weber, J. Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor. Antiviral Research 2021, 185 (January), nestránkováno.

Doleželová, E.; Downey, A. Michael; Hocek, M.; Nguyen, V. Hai; Pohl, R.; Rožánková, S.; Slapničková, M.; Tichý, M.; Tloušťová, E.; Zíková, A. Synthesis and anti-trypanosomal activity of 3'-fluororibonucleosides derived from 7-deazapurine nucleosides. Bioorganic and Medicinal Chemistry Letters 2021, 40 (May 15 2021), nestránkováno.

Doleželová, E.; Džubák, P.; Gurská, S.; Hajdúch, M.; Hocek, M.; Krajczyk, A.; Milisavljević, N.; Perlíková, P.; Slavětínská, L. Poštová; Slapničková, M.; et al. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS Infectious Diseases 2021, 7 (4), 917-926.

Catanzano, O.; Conte, C.; Fraix, A.; Kalydi, E.; Kasal, P.; Payamifar, S.; Quaglia, F.; Seggio, M.; Sortino, S. Visible light-activatable cyclodextrin-conjugates for the efficient delivery of nitric oxide with fluorescent reporter and their inclusion complexes with betaxolol. New Journal of Chemistry 2021, 45 (19), 8449-8455.

Drastík, M.; Holas, O.; Hroch, M.; Hutníková, M.; Kašpar, M.; Kudová, E.; Mičuda, S.; Pandey, A. V.; Pávek, P.; Smutný, T.; et al. 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism. Journal of Steroid Biochemistry and Molecular Biology 2020, 202 (September), nestránkováno DOI: 10.1016/j.jsbmb.2020.105702.

Drastík, M.; Holas, O.; Hroch, M.; Hutníková, M.; Kašpar, M.; Kudová, E.; Mičuda, S.; Pandey, A. V.; Pávek, P.; Smutný, T.; et al. 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism. Journal of Steroid Biochemistry and Molecular Biology 2020, 202 (September), nestránkováno DOI: 10.1016/j.jsbmb.2020.105702.

Brynda, J.; Fanfrlík, J.; Hadzima, M.; Hánová, I.; Horn, M.; Houštecká, R.; Lepšík, M.; Majer, P.; Mareš, M.; Mertlíková-Kaiserová, H.; et al. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of Medicinal Chemistry 2020, 63 (4), 1576-1596 DOI: 10.1021/acs.jmedchem.9b01351.