News

Our new study on the heme sensor histidine kinase, AfGcHK has been accepted

December 30, 2019
Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor AfGcHK abolishes bacterial signal transduction

Tereza Skalova, Alzbeta Lengalova, Jan Dohnalek, Karl Harlos, Peter Mihalcin, Petr Kolenko, Martin Stranav, Jan Blaha, Toru Shimizu and Markéta Martínková (2020) in Journal of Biological Chemistry DOI: 10.1074/jbc.RA119.011574

Marketa was invited by The Embassy of Japan in the Czech Republic to reception at Ambassador’s Residence (Mr. Kaoru SHIMAZAKI) as a member of the Network of Alumni and Students of Japanese Schools.

December 4, 2019

Our review on heme sensor proteins has been accepted

October 26, 2019

Heme: Emergent roles of heme in signal transduction, functional regulation and as catalytic centres

Shimizu T., Lengalova A., Martínek V., Martínková M. (2019)

in Chemical  Society Reviews (Royal Society of Chemistry), 48 (24), 5624-5657 DOI: 10.1039/c9cs00268e, IF2017 = 40.443

We published a new paper on diguanylate cyclase (YddV)

September 9, 2019

Unlabelled Image

Kinetic analysis of a globin-coupled diguanylate cyclase, YddV: Effects of heme iron redox state, axial ligands, and heme distal mutations on catalysis

in Journal of Inorganic Biochemistry (Elsevier) DOI:  doi.org/10.1016/j.jinorgbio.2019.110833

 

Group photo 2019

July 17, 209

Dr. David Hanna (School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, USA) held a lecture

July 23, 2019
  • Lecture title was: Characterization and Use of Genetically Encoded Fluorescent Heme Sensors to Interrogate Heme Trafficking, Dynamics, and Signaling

Jakub and Peter successfully finalized their Master of Science studies. Jakub will continue as a PhD student and Peter will work for a private chemical company. Congratulations!

July 19, 2019

Alzbeta attended the 44th FEBS Congress in Krakow (Poland)

July 6 - 11, 2019

Veronika successfully defended her PhD thesis

September 10, 2018

Jakub attended the XX International Conference on Oxygen Binding and Sensing Proteins in Barcelona (Spain).

September 3 - 6, 2018