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Unraveling the cell - cell communication
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Faculty of Science, Charles University
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Eavesdropping the signaling crosstalk
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Laboratory of Intercellular Communication

Research area

We are focused on basic biological questions from the fields of developmental biology and genetic disorders.

In our research, we use human cell lines, omics, and newly developed genetic mouse models.


We strive to gain a better mechanistic insight into the processes co-regulated by direct protein-protein interaction between components of Notch and Wnt pathways and Non-canonical Notch-ligand mediated signaling in development, homeostasis and disease.


  • New preprint is out!
    Please have a look at what we learned when dissecting the liver and T cell […]
  • Welcome Eliška and Matouš
    We are very excited about having two new lab members a CUNI bachelor student Eliška […]
  • Congratulations Hana!
    The whole lab was celebrating Hana’s bachelor thesis defence, the very first in our group […]

credits for maseklab logo: Igor Cervenka. PhD