Publications

Malkov, A. V.; Westwater, M. - M.; Gutnov, A.; Ramírez-López, P.; Friscourt, F.; Kadlcikova, A.; Hodačová, J.; Rankovic, Z.; Kotora, M.; Kočovský, P. New pyridine N-oxides as chiral organocatalysts in the asymmetric allylation of aromatic aldehydes. Tetrahedron 2008, 64 (49), 11335-11348 DOI: 10.1016/j.tet.2008.08.084.

Riedl, J.; Ménová, P.; Pohl, R.; Orság, P.; Fojta, M.; Hocek, M. GFP-like Fluorophores as DNA Labels for Studying DNA–Protein Interactions. The Journal of Organic Chemistry 2012, 77 (18), 8287-8293 DOI: 10.1021/jo301684b.

Riedl, J.; Pohl, R.; Ernsting, N. P.; Orság, P.; Fojta, M.; Hocek, M. Labelling of nucleosides and oligonucleotides by solvatochromic 4-aminophthalimide fluorophore for studying DNA–protein interactions. Chemical Science 2012, 3 (9), 2797 DOI: 10.1039/c2sc20404e.

Raindlová, V.; Pohl, R.; Klepetářová, B.; Havran, L.; Šimková, E.; Horáková, P.; Pivonkova, H.; Fojta, M.; Hocek, M. Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling. ChemPlusChem 2012, 77 (8), 652-662 DOI: 10.1002/cplu.201200056.

Dadová, J.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Aqueous Heck Cross-Coupling Preparation of Acrylate-Modified Nucleotides and Nucleoside Triphosphates for Polymerase Synthesis of Acrylate-Labeled DNA. The Journal of Organic Chemistry 2013, 78 (19), 9627-9637 DOI: 10.1021/jo4011574.

Balintová, J.; Plucnara, M.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases. Chemistry - A European Journal 2013, 19 (38), 12720-12731 DOI: 10.1002/chem.201301868.

Fanfrlík, J.; Kolář, M.; Kamlar, M.; Hurný, D.; Ruiz, F. X.; Cousido-Siah, A.; Mitschler, A.; Řezáč, J.; Munusamy, E.; Lepšík, M.; et al. Modulation of Aldose Reductase Inhibition by Halogen Bond Tuning. ACS Chemical Biology 2013, 8 (11), 2484-2492 DOI: 10.1021/cb400526n.

Ménová, P.; Cahová, H.; Plucnara, M.; Havran, L.; Fojta, M.; Hocek, M. Polymerase synthesis of oligonucleotides containing a single chemically modified nucleobase for site-specific redox labelling. Chemical Communications 2013, 49 (41), 4652 DOI: 10.1039/c3cc41438h.

Kalachova, L.; Pohl, R.; Bednárová, L.; Fanfrlík, J.; Hocek, M. Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations. Org. Biomol. Chem. 2013, 11 (1), 78-89 DOI: 10.1039/C2OB26881G.

Dadová, J.; Orság, P.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M. Vinylsulfonamide and Acrylamide Modification of DNA for Cross-linking with Proteins. Angewandte Chemie International Edition 2013, 52 (40), 10515-10518 DOI: 10.1002/anie.201303577.

Kielkowski, P.; Fanfrlík, J.; Hocek, M. 7-Aryl-7-deazaadenine 2′-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations. Angewandte Chemie International Edition 2014, 53 (29), 7552-7555 DOI: 10.1002/anie.201404742.

Danhel, A.; Raindlová, V.; Havran, L.; Pivonkova, H.; Hocek, M.; Fojta, M. Electrochemical behaviour of 2,4-dinitrophenylhydrazi(o)ne as multi-redox centre DNA label at mercury meniscus modified silver solid amalgam electrode. Electrochimica Acta 2014, 126, 122-131 DOI: 10.1016/j.electacta.2013.09.147.

Simonova, A.; Balintová, J.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Methoxyphenol and Dihydrobenzofuran as Oxidizable Labels for Electrochemical Detection of DNA. ChemPlusChem 2014, n/a-n/a DOI: 10.1002/cplu.201402194.

Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; et al. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (20), 8268-8279 DOI: 10.1021/jm500497v.

Danhel, A.; Raindlová, V.; Havran, L.; Barek, J.; Hocek, M.; Fojta, M. Voltammetric Study of dsDNA Modified by Multi-redox Label Based on N-methyl-4-hydrazino-7-nitrobenzofurazan. Electrochimica Acta 2014, 129, 348-357 DOI: 10.1016/j.electacta.2014.02.137.

Balintová, J.; Špaček, J.; Pohl, R.; Brázdová, M.; Havran, L.; Fojta, M.; Hocek, M. Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions. Chem. Sci. 2015, 6 (1), 575-587 DOI: 10.1039/C4SC01906G.

Dadová, J.; Vrábel, M.; Adámik, M.; Brázdová, M.; Pohl, R.; Fojta, M.; Hocek, M. Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking. Chemistry - A European Journal 2015, 21 (45), 16091-16102 DOI: 10.1002/chem.201502209.

Popr, M.; Filippov, S. K.; Matushkin, N.; Dian, J.; Jindřich, J. Properties of cationic monosubstituted tetraalkylammonium cyclodextrin derivatives – their stability, complexation ability in solution or when deposited on solid anionic surface. Beilstein Journal of Organic Chemistry 2015, 11, 192-199 DOI: 10.3762/bjoc.11.20.

Cahová, H.; Panattoni, A.; Kielkowski, P.; Fanfrlík, J.; Hocek, M. 5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs. ACS Chemical Biology 2016, 11 (11), 3165-3171 DOI: 10.1021/acschembio.6b00714.

Olszewska, A.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M. Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins. Bioconjugate Chemistry 2016, 27 (9), 2089-2094 DOI: 10.1021/acs.bioconjchem.6b00342.

Matoušová, E.; Koukal, P.; Formánek, B.; Kotora, M. Enantioselective Synthesis of the Unsaturated Fragment of Callyspongiolide. Organic Letters 2016, 18 (21), 5656-5659 DOI: 10.1021/acs.orglett.6b02897.

Benkovics, G.; Hodek, O.; Havlikova, M.; Bosakova, Z.; Coufal, P.; Malanga, M.; Fenyvesi, E.; Darcsi, A.; Beni, S.; Jindřich, J. Supramolecular structures based on regioisomers of cinnamyl-α-cyclodextrins – new media for capillary separation techniques. Beilstein Journal of Organic Chemistry 2016, 12, 97-109 DOI: 10.3762/bjoc.12.11.

Korotvička, A.; Frejka, D.; Hampejsová, Z.; Císařová, I.; Kotora, M. Synthesis of Phenanthridines via a Rhodium-Catalyzed C–C Bond Cleavage Reaction of Biphenylene with Nitriles. Synthesis 2016, 48 (07), 987-996 DOI: 10.1055/s-0035-1561343.

Danhel, A.; Trosanova, Z.; Balintová, J.; Havran, L.; Hocek, M.; Barek, J.; Fojta, M. Voltammetric analysis of 5-(4-Azidophenyl)-2′-deoxycytidine nucleoside and azidophenyl-labelled single- and double-stranded DNAs. Electrochimica Acta 2016, 215, 72-83 DOI: 10.1016/j.electacta.2016.08.096.

Roeser, J.; Prill, D.; Bojdys, M. J.; Fayon, P.; Trewin, A.; Fitch, A. N.; Schmidt, M. U.; Thomas, A. Anionic silicate organic frameworks constructed from hexacoordinate silicon centres. Nature Chemistry 2017, 9 (10), 977-982 DOI: 10.1038/NCHEM.2771.