Publications

Hocek, M. Synthesis of Base-Modified 2′-Deoxyribonucleoside Triphosphates and Their Use in Enzymatic Synthesis of Modified DNA for Applications in Bioanalysis and Chemical Biology. The Journal of Organic Chemistry 2014, 79 (21), 9914-9921 DOI: 10.1021/jo5020799.

Hocek, M.; Jauset-Rubio, M.; Kodr, D.; Ortiz, M.; O'Sullivan, C. Kathleen; Simonova, A. Solid-phase recombinase polymerase amplification using ferrocene-labelled dNTPs for electrochemical detection of single nucleotide polymorphisms. Biosensors and Bioelectronics 2022, 198 (February), nestránkováno.

Hessler, F.; Císařová, I.; Sedlák, D.; Bartůněk, P.; Kotora, M. Synthesis of Ferrocenestrone: the First Metallocene Based Steroid Analogue. Chemistry - A European Journal 2012, 18 (18), 5515-5518 DOI: 10.1002/chem.201200687.

Hessler, F.; Korotvička, A.; Nečas, D.; Valterová, I.; Kotora, M. Syntheses of a Flobufen Metabolite and Dapoxetine Based on Enantioselective Allylation of Aromatic Aldehydes: Syntheses of a Flobufen Metabolite and Dapoxetine. European Journal of Organic Chemistry 2014, 2014 (12), 2543-2548 DOI: 10.1002/ejoc.201301899.

Hejdánek, J.; Hodek, J.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Pachl, P.; Radilová, K.; Řezáčová, P.; Weber, J. Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor. Antiviral Research 2021, 185 (January), nestránkováno.

Fleuti, M. Heidi; Quirante, T. Sanchez; Slavětínská, L. Poštová; Tloušťová, E.; Tichý, M.; Gurská, S.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides. ACS Omega 2024, 9 (18), 20557-20570.

Fadeev, A.; Manca, G.; Kotora, M. Selective Catalytic Cross-Cyclotrimerization En Route to1,4-Diborylated Benzenes and Their Synthetic Transformations. Advanced Synthesis and Catalysis 2023, 365 (7), 965-970.

Eignerová, B.; Slavíková, B.; Buděšínský, M.; Dračínský, M.; Klepetářová, B.; Št’astná, E.; Kotora, M. Synthesis of Fluorinated Brassinosteroids Based on Alkene Cross-Metathesis and Preliminary Biological Assessment. Journal of Medicinal Chemistry 2009, 52 (18), 5753-5757 DOI: 10.1021/jm900495f.

Eignerová, B.; Janoušek, Z.; Dračínský, M.; Kotora, M. Synthesis of Perfluoroalkylated Carboranes by Cross-Metathesis of Allylcarboranes and Perfluoroalkylpropenes. Synlett 2010, 2010 (06), 885-888 DOI: 10.1055/s-0029-1219546.

Eignerová, B.; Sedlák, D.; Dračínský, M.; Bartůněk, P.; Kotora, M. Synthesis and Biochemical Characterization of a Series of 17α-Perfluoroalkylated Estradiols as Selective Ligands for Estrogen Receptor α. Journal of Medicinal Chemistry 2010, 53 (19), 6947-6953 DOI: 10.1021/jm100563h.

Džubák, P.; Gurska, S.; Hajdúch, M.; Hocek, M.; Pavliš, P.; Pohl, R.; Tichý, M.; Yang, C. Synthesis, Photophysical Properties, and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides. Journal of Organic Chemistry 2020, 85 (12), 8085-8101 DOI: 10.1021/acs.joc.0c00927.

Dziuba, D.; Pospíšil, P.; Matyašovský, J.; Brynda, J.; Nachtigallová, D.; Rulíšek, L.; Pohl, R.; Hof, M.; Hocek, M. Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions. Chem. Sci. 2016, 7 (9), 5775-5785 DOI: 10.1039/C6SC02548J.

A. Downey, M.; Pohl, R.; Roithová, J.; Hocek, M. Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism. Chemistry-a European Journal 2017, 23 (16), 3910-3917 DOI: 10.1002/chem.201604955.

Doleželová, E.; Džubák, P.; Gurská, S.; Hajdúch, M.; Hocek, M.; Krajczyk, A.; Milisavljević, N.; Perlíková, P.; Slavětínská, L. Poštová; Slapničková, M.; et al. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS Infectious Diseases 2021, 7 (4), 917-926.

Doleželová, E.; Downey, A. Michael; Hocek, M.; Nguyen, V. Hai; Pohl, R.; Rožánková, S.; Slapničková, M.; Tichý, M.; Tloušťová, E.; Zíková, A. Synthesis and anti-trypanosomal activity of 3'-fluororibonucleosides derived from 7-deazapurine nucleosides. Bioorganic and Medicinal Chemistry Letters 2021, 40 (May 15 2021), nestránkováno.

Dočekal, V.; Melaimi, M.; Petrželová, S.; Veselý, J.; Yan, X.; Bertrand, G. Synthesis of enantiopure 1,2,3-triazolylidene-type mesoionic carbene (MIC) conjugate acids featuring a rigid bicyclic scaffold. Organic Chemistry Frontiers 2024, 11 (8), 2178-2181.

Dhami, K.; Malyshev, D. A.; Ordoukhanian, P.; Kubelka, T.; Hocek, M.; Romesberg, F. E. Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet. Nucleic Acids Research 2014, 42 (16), 10235-10244 DOI: 10.1093/nar/gku715.

Císařová, I.; Hara, S.; Kotora, M.; Topolovčan, N.; Tošner, Z. A Study of Polarization and Directing Effects of Unsymmetrical Alkynes Using Regioselective Pd-Catalyzed Bromoallylation. European Journal of Organic Chemistry 2020, 2020 (2), 234-240 DOI: 10.1002/ejoc.201901476.

Císařová, I.; Dočekal, V.; Gyepes, R.; Hrabovský, J.; Koberová, T.; Rios, R.; Veselý, J.; Vopálenská, A. Stereoselective cyclopropanation of boron dipyrromethene (BODIPY) derivatives by an organocascade reaction. Advanced Synthesis and Catalysis 2022, 364 (5), 930-937.

Císařová, I.; Henriksson, E.; Kamlar, M.; Malo, M.; Sunden, H. Synthesis of cis-Oriented Vicinal Diphenylethylenes through a Lewis Acid-Promoted Annulation of Oxotriphenylhexanoates. Journal of Organic Chemistry 2021, 86 (13), 8660-8671.

Chapuis, H.; Kubelka, T.; Joubert, N.; Pohl, R.; Hocek, M. Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2′-Deoxyribonucleosides. European Journal of Organic Chemistry 2012, 2012 (9), 1759-1767 DOI: 10.1002/ejoc.201101662.

Ceban, V.; Putaj, P.; Meazza, M.; Pitak, M. B.; Coles, S. J.; Vesely, J.; Rios, R. Synergistic catalysis: highly diastereoselective benzoxazole addition to Morita–Baylis–Hillman carbonates. Chemical Communications 2014, 50 (56), 7447 DOI: 10.1039/c4cc00728j.

Bursová, M.; Čabala, R.; Hložek, T.; Jelinek, I.; Štícha, M.; Tůma, P. Sensitive CE-MS method for monitoring of riociguat and desmethylriociguat levels in human serum. Electrophoresis 2020, 41 (18-19), 1564-1567 DOI: 10.1002/elps.202000135.

Brynda, J.; Das, V.; Dvořanová, J.; Džubák, P.; Anwar, S. El; Fábry, M.; Grüner, B.; Gurska, S.; Hajdúch, M.; Havránek, M.; et al. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. European Journal of Medicinal Chemistry 2020, 200 (August), nestránkováno DOI: 10.1016/j.ejmech.2020.112460.

Bouřa, E.; Dejmek, M.; Chalupská, D.; Klíma, M.; Matoušová, M.; Mertlíková-Kaiserová, H.; Misehe, M.; Nencka, R.; Šála, M. Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorganic and Medicinal Chemistry Letters 2022, 76 (November), nestránkováno.