Publications

Bosáková, A.; Perlíková, P.; Tichý, M.; Pohl, R.; Hocek, M. 6-Aryl-4-amino-pyrimido[4,5-b]indole 2′-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study. Bioorganic & Medicinal Chemistry 2016, 24 (19), 4528-4535 DOI: 10.1016/j.bmc.2016.07.054.

Perlikova, P.; Rylova, G.; Naus, P.; Elbert, T.; Tloustova, E.; Bourderioux, A.; Slavetinska, L. P.; Motyka, K.; Dolezal, D.; Znojek, P.; et al. 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action. Molecular Cancer Therapeutics 2016, 15 (5), 922-937 DOI: 10.1158/1535-7163.MCT-14-0933.

Topolovčan, N.; Panov, I.; Kotora, M. Bisallylation of Zirconacyclopentenes and Ring-Closing Metathesis: A Route to Eight-Membered-Ring Compounds. Synlett 2016, 27 (03), 432-436 DOI: 10.1055/s-0035-1560587.

Kučerová, G.; Kalíková, K.; Procházková, H.; Popr, M.; Jindřich, J.; Coufal, P.; Tesařová, E. Chromatographic Characterization of a New Cationic β-CD Based Stationary Phase Prepared by Dynamic Coating. Chromatographia 2016, 79 (9-10), 529-536 DOI: 10.1007/s10337-016-3050-z.

Tsybizova, A.; Roithová, J. Copper-catalyzed reactions: Research in the gas phase: COPPER CATALYSIS. Mass Spectrometry Reviews 2016, 35 (1), 85-110 DOI: 10.1002/mas.21464.

Nakatani, K.; Tor, Y.; Dadová, J.; Cahová, H.; Hocek, M. Polymerase Synthesis of Base-Modified DNA; Springer International Publishing: Cham, 2016; Vol. 31, pp 123-144.

Makukhin, N.; Tretyachenko, V.; Moskovitz, J.; Míšek, J. A Ratiometric Fluorescent Probe for Imaging of the Activity of Methionine Sulfoxide Reductase A in Cells. Angewandte Chemie International Edition 2016, 55 (41), 12727-12730 DOI: 10.1002/anie.201605833.

Humpl, M.; Tauchman, J.; Topolovčan, N.; Kretschmer, J.; Hessler, F.; Císařová, I.; Kotora, M.; Vesely, J. Stereoselective Synthesis of Ezetimibe via Cross-Metathesis of Homoallylalcohols and α-Methylidene-β-Lactams. The Journal of Organic Chemistry 2016, 81 (17), 7692-7699 DOI: 10.1021/acs.joc.6b01406.

Humpl, M.; Tauchman, J.; Topolovčan, N.; Kretschmer, J.; Hessler, F.; Císařová, I.; Kotora, M.; Vesely, J. Stereoselective Synthesis of Ezetimibe via Cross-Metathesis of Homoallylalcohols and α-Methylidene-β-Lactams. The Journal of Organic Chemistry 2016, 81 (17), 7692-7699 DOI: 10.1021/acs.joc.6b01406.

Danhel, A.; Trosanova, Z.; Balintová, J.; Havran, L.; Hocek, M.; Barek, J.; Fojta, M. Voltammetric analysis of 5-(4-Azidophenyl)-2′-deoxycytidine nucleoside and azidophenyl-labelled single- and double-stranded DNAs. Electrochimica Acta 2016, 215, 72-83 DOI: 10.1016/j.electacta.2016.08.096.

Gergelitsová, I.; Tauchman, J.; Císařová, I.; Veselý, J. Bifunctional (Thio)urea–Phosphine Organocatalysts Derived from d-Glucose and α-Amino Acids and Their Application to the Enantio­selective Morita–Baylis–Hillman Reaction. Synlett 2015, 26 (19), 2690-2696 DOI: 10.1055/s-0035-1560931.

Gray, A.; Tsybizova, A.; Roithova, J. Carboxylate-assisted C–H activation of phenylpyridines with copper, palladium and ruthenium: a mass spectrometry and DFT study. Chem. Sci. 2015, 6 (10), 5544-5553 DOI: 10.1039/C5SC01729G.

Topolovčan, N.; Panov, I.; Kotora, M. Reaction of Bicyclic Zirconacyclopentenes with Aldehydes and a Potential Pathway to Condensed 5-7-6(Ar) Ring Systems: Reaction of Bicyclic Zirconacyclopentenes with Aldehydes. European Journal of Organic Chemistry 2015, 2015 (13), 2868-2878 DOI: 10.1002/ejoc.201500248.

Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.

Klečka, M.; Slavětínská, L. Poštová; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides. Med. Chem. Commun. 2015, 6 (4), 576-580 DOI: 10.1039/C4MD00492B.

Tokarenko, A.; Slavětínská, L. Poštová; Klepetářová, B.; Hocek, M. Synthesis of Benzene and Pyridine 2-C-Methyl-C-ribonucleosides and -nucleotides. European Journal of Organic Chemistry 2015, 2015 (36), 7962-7983 DOI: 10.1002/ejoc.201501219.

Bednaříková, T.; Tošner, Z.; Horský, J.; Jindřich, J. Synthesis of C 3 -symmetric tri(alkylamino) guests and their interaction with cyclodextrins. Journal of Inclusion Phenomena and Macrocyclic Chemistry 2015, 81 (1-2), 141-152 DOI: 10.1007/s10847-014-0443-1.

Šnajdr, I.; Janoušek, Z.; Takagaki, M.; Císařová, I.; Hosmane, N. S.; Kotora, M. Alpha (α-) and beta (β-carboranyl-C-deoxyribosides: Syntheses, structures and biological evaluation. European Journal of Medicinal Chemistry 2014, 83, 389-397 DOI: 10.1016/j.ejmech.2014.06.005.

Tsybizova, A.; Schröder, D.; Roithová, J.; Henke, A.; Šrogl, J. Gas-phase studies of copper catalyzed aerobic cross coupling of thiol esters and arylboronic acids: REACTION MECHANISMS. Journal of Physical Organic Chemistry 2014, 27 (3), 198-203 DOI: 10.1002/poc.3262.

Tumova, L.; Pombinho, A. R.; Vojtechova, M.; Stancikova, J.; Gradl, D.; Krausova, M.; Sloncova, E.; Horazna, M.; Kriz, V.; Machonova, O.; et al. Monensin inhibits canonical wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice. Molecular cancer therapeutics 2014, 13 (4), 812-822 DOI: 10.1158/1535-7163.MCT-13-0625.

Putaj, P.; Tichá, I.; Císařová, I.; Vesely, J. One-Pot Preparation of Chiral Carbacycles from Morita-Baylis-Hillman Carbonates by an Asymmetric Allylic Alkylation/Olefin Metathesis Sequence: One-Pot Preparation of Chiral Carbacycles. European Journal of Organic Chemistry 2014, 2014 (30), 6615-6620 DOI: 10.1002/ejoc.201402899.

Tsybizova, A.; Remeš, M.; Vesely, J.; Hybelbauerová, S.; Roithová, J. Organocatalytic Preparation of Substituted Cyclopentanes: A Mechanistic Study. The Journal of Organic Chemistry 2014, 79 (4), 1563-1570 DOI: 10.1021/jo4022106.

Tsybizova, A.; Ryland, B. L.; Tsierkezos, N.; Stahl, S. S.; Roithová, J.; Schröder, D. Speciation Behavior of Copper(II) Acetate in Simple Organic Solvents - Revealing the Effect of Trace Water: Speciation Behavior of Cu(II) Acetate in Simple Organic Solvents. European Journal of Inorganic Chemistry 2014, 2014 (8), 1407-1412 DOI: 10.1002/ejic.201400036.

Tsybizova, A.; Ryland, B. L.; Tsierkezos, N.; Stahl, S. S.; Roithová, J.; Schröder, D. Speciation Behavior of Copper(II) Acetate in Simple Organic Solvents - Revealing the Effect of Trace Water: Speciation Behavior of Cu(II) Acetate in Simple Organic Solvents. European Journal of Inorganic Chemistry 2014, 2014 (8), 1407-1412 DOI: 10.1002/ejic.201400036.

Nauš, P.; Caletková, O.; Konečný, P.; Džubák, P.; Bogdanová, K.; Kolář, M.; Vrbková, J.; Slavětínská, L.; Tloušt’ová, E.; Perlíková, P.; et al. Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (3), 1097-1110 DOI: 10.1021/jm4018948.