Publications

Břehová, P.; Česnek, M.; Dračínský, M.; Chaloupecká, E.; Janeba, Z.; Mertlíková-Kaiserová, H.; Skácel, J.; Soto-Velasquez, M. P.; Tloušťová, E.; Watts, V. J. Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases. European Journal of Medicinal Chemistry 2021, 222 (October 15 2021), nestránkováno.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.

Katekomol, P.; Roeser, J.; Bojdys, M.; Weber, J.; Thomas, A. Covalent Triazine Frameworks Prepared from 1,3,5-Tricyanobenzene. Chemistry of Materials 2013, 25 (9), 1542-1548 DOI: 10.1021/cm303751n.

Baszczyňski, O.; Dračínský, M.; Dvořáková, A.; Hodek, J.; Chalupský, K.; Janeba, Z.; Kalčic, F.; Kaiserová, H. Mertlíkov; Strmeň, T.; Šebestík, J.; et al. Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties. Journal of Medicinal Chemistry 2021, 64 (22), 16425-16449.

Gülak, S.; Štěpánek, O.; Malberg, J.; Rad, B. Rezaei; Kotora, M.; Wolf, R.; von Wangelin, A. Jacobi. Highly chemoselective cobalt-catalyzed biaryl coupling reactions. Chem. Sci. 2013, 4 (2), 776-784 DOI: 10.1039/C2SC21667A.

Machara, A.; Werner, L.; Endoma-Arias, M. Ann; D. Cox, P.; Hudlicky, T. Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium-Catalyzed N-Demethylation/Acylation and/or Concomitant O-Demethylation. Advanced Synthesis & Catalysis 2012, 354 (4), 613-626 DOI: 10.1002/adsc.201100807.

Bojdys, M. J.; Wohlgemuth, S. A.; Thomas, A.; Antonietti, M. Ionothermal Route to Layered Two-Dimensional Polymer-Frameworks Based on Heptazine Linkers. Macromolecules 2010, 43 (16), 6639-6645 DOI: 10.1021/ma101008c.

Malkov, A. V.; Westwater, M. - M.; Gutnov, A.; Ramírez-López, P.; Friscourt, F.; Kadlcikova, A.; Hodačová, J.; Rankovic, Z.; Kotora, M.; Kočovský, P. New pyridine N-oxides as chiral organocatalysts in the asymmetric allylation of aromatic aldehydes. Tetrahedron 2008, 64 (49), 11335-11348 DOI: 10.1016/j.tet.2008.08.084.

Nakanishi, T.; Weber, J.; Bojdys, M. J.; Thomas, A. Polymeric Frameworks: Toward Porous Semiconductors; John Wiley & Sons, Inc.: Hoboken, NJ, USA, 2011; pp 119-154.

Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.; Andraos, J. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency Metrics. The Journal of Organic Chemistry 2011, 76 (24), 10050-10067 DOI: 10.1021/jo2018872.

Werner, L.; Machara, A.; Hudlicky, T. Short Chemoenzymatic Azide-Free Synthesis of Oseltamivir (Tamiflu): Approaching the Potential for Process Efficiency. Advanced Synthesis & Catalysis 2010, 352 (1), 195-200 DOI: 10.1002/adsc.200900844.

Hejdánek, J.; Hodek, J.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Pachl, P.; Radilová, K.; Řezáčová, P.; Weber, J. Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor. Antiviral Research 2021, 185 (January), nestránkováno.

Tichý, M.; Pohl, R.; Tloušt’ová, E.; Weber, J.; Bahador, G.; Lee, Y. - J.; Hocek, M. Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2013, 21 (17), 5362-5372 DOI: 10.1016/j.bmc.2013.06.011.

Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.

Werner, L.; Machara, A.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Synthesis of Buprenorphine from Oripavine via N-Demethylation of Oripavine Quaternary Salts. The Journal of Organic Chemistry 2011, 76 (11), 4628-4634 DOI: 10.1021/jo200567n.

Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. Ann; Duchek, J.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Unexpected N -Demethylation of Oxymorphone and Oxycodone N -Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2706-2712 DOI: 10.1002/adsc.201200676.

Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. Ann; Duchek, J.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Unexpected N -Demethylation of Oxymorphone and Oxycodone N -Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2706-2712 DOI: 10.1002/adsc.201200676.

Albiñana, C. Berenguer; Brynda, J.; Fanfrlík, J.; Flieger, M.; Hodek, J.; Karlukova, E.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Majer, P.; et al. Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors. European Journal of Medicinal Chemistry 2020, 208 (December), nestránkováno DOI: 10.1016/j.ejmech.2020.112754.