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Host – Pathogen Interactions
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Shaping adaptive immune response by antigen presentation
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Faculty of Science, Charles University
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Laboratory of Microbial Immunology

Our focus lies in unraveling the intricate cell fate decisions guided by antigen presentation within the immune system. We delve into the realm of antigen-presenting cells, exploring their biology, interactions with various cell types, and the intricate mechanisms they employ to modulate T-cell responses, be it in response to pathogens, commensal microorganisms, or self-structures. Our overarching goal is to gain a comprehensive understanding of the underlying mechanisms that give rise to immune-related pathologies. By doing so, we aim to pave the way for the development of more effective treatment strategies in the future.

Research area

Host-pathogen interactions, antigen presenting cells, adaptive immunity.