Welcome to the Laboratory of Regulatory RNAs
The lab started in January 2024
Our research is focused on small non-coding RNAs involved in regulation of bacterial transcription. We are mainly interested in RNAs that interact with RNA polymerase. We have developed the RIP-seq method to identify these regulatory RNAs across a wide range of bacterial species. Our long-term goal is to elucidate the function(s) of these RNAs and and answer whether they could be utilized in the future to develop specific RNA antibiotics targeting individual bacterial species.
News
- Isolation of environmental mycobacteria
Violka and Silvie, together with our colleagues from České Budějovice, optimized the protocol for isolating… Read more: Isolation of environmental mycobacteria - Excursion to a clinical laboratory
In April, we organized a field trip to a clinical microbiology lab for the students… Read more: Excursion to a clinical laboratory - Three Bachelor students successfully defended
Eliška Mikesková, Lucie Zahradníčková and Adam Hoško defended their Bachelor thesis in June 2025. Congratulations… Read more: Three Bachelor students successfully defended
Visit the website with our NGS data
Together with Marek Schwarz from the Laboratory of Bioinformatics at Institute of Microbiology, we decided to create a webpage with integrated igv genome browser for Mycobacterium smegmatis ChIP-seq, RNA-seq and RIP-seq visualization.