Welcome to the Laboratory of Regulatory RNAs
The lab started in January 2024
Our research is focused on small non-coding RNAs involved in regulation of bacterial transcription. We are mainly interested in RNAs that interact with RNA polymerase. We have developed the RIP-seq method to identify these regulatory RNAs across a wide range of bacterial species. Our long-term goal is to elucidate the function(s) of these RNAs and and answer whether they could be utilized in the future to develop specific RNA antibiotics targeting individual bacterial species.
News
- Microbiology PhD forum
On 21 September, together with the Czechoslovak Society for Microbiology, we are organizing a meeting… Read more: Microbiology PhD forum - Never Too Early to Start Cloning
Matilda Vyhnálková, a high school student, worked in our lab during 2025 and 2026. She… Read more: Never Too Early to Start Cloning - Two Bachelor students successfully defended
Julie and Ota defended their bachelor’s theses (“Toxin-antitoxin systems in mycobacteria: molecular mechanisms and biological… Read more: Two Bachelor students successfully defended
Visit the website with our NGS data
Together with Marek Schwarz from the Laboratory of Bioinformatics at Institute of Microbiology, we decided to create a webpage with integrated igv genome browser for Mycobacterium smegmatis ChIP-seq, RNA-seq and RIP-seq visualization.