Publications

Found 321 results
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2015
Balintová, J.; Špaček, J.; Pohl, R.; Brázdová, M.; Havran, L.; Fojta, M.; Hocek, M. Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions. Chem. Sci. 2015, 6 (1), 575-587 DOI: 10.1039/C4SC01906G.
Dadová, J.; Vrábel, M.; Adámik, M.; Brázdová, M.; Pohl, R.; Fojta, M.; Hocek, M. Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking. Chemistry - A European Journal 2015, 21 (45), 16091-16102 DOI: 10.1002/chem.201502209.
Olszewska, A.; Dadová, J.; Mačková, M.; Hocek, M. Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. Bioorganic & Medicinal Chemistry 2015, 23 (21), 6885-6890 DOI: 10.1016/j.bmc.2015.09.051.
Šnajdr, I.; Parkan, K.; Hessler, F.; Kotora, M. Cross-metathesis reaction of α- and β-vinyl C -glycosides with alkenes. Beilstein Journal of Organic Chemistry 2015, 11, 1392-1397 DOI: 10.3762/bjoc.11.150.
A. Downey, M.; Richter, C.; Pohl, R.; Mahrwald, R.; Hocek, M. Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose. Organic Letters 2015, 17 (18), 4604-4607 DOI: 10.1021/acs.orglett.5b02332.
Ménová, P.; Dziuba, D.; Güixens-Gallardo, P.; Jurkiewicz, P.; Hof, M.; Hocek, M. Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction. Bioconjugate Chemistry 2015, 26 (2), 361-366 DOI: 10.1021/acs.bioconjchem.5b00006.
Ménová, P.; Dziuba, D.; Güixens-Gallardo, P.; Jurkiewicz, P.; Hof, M.; Hocek, M. Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction. Bioconjugate Chemistry 2015, 26 (2), 361-366 DOI: 10.1021/acs.bioconjchem.5b00006.
Sabat, N.; Slavětínská, L. Poštová; Hocek, M. Ir-catalyzed C–H silylations of phenyldeazapurines. Tetrahedron Letters 2015, 56 (49), 6860-6862 DOI: 10.1016/j.tetlet.2015.10.089.
Klečka, M.; Slavětínská, L. Poštová; Hocek, M. Modification of Pyrrolo[2,3-d]pyrimidines by C-H Borylation Followed by Cross-Coupling or Other Transformations: Synthesis of 6,8-Disubstituted 7-Deazapurine Bases. European Journal of Organic Chemistry 2015, 2015 (36), 7943-7961 DOI: 10.1002/ejoc.201501177.
Mačková, M.; Boháčová, S.; Perlíková, P.; Slavětínská, L. Poštová; Hocek, M. Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine Nucleobases. ChemBioChem 2015, 16 (15), 2225-2236 DOI: 10.1002/cbic.201500315.
Dziuba, D.; Pohl, R.; Hocek, M. Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins. Chem. Commun. 2015, 51 (23), 4880-4882 DOI: 10.1039/C5CC00530B.
Jašíková, L.; Anania, M.; Hybelbauerová, S.; Roithová, J. Reaction Intermediates Kinetics in Solution Investigated by Electrospray Ionization Mass Spectrometry: Diaurated Complexes. Journal of the American Chemical Society 2015, 137 (42), 13647-13657 DOI: 10.1021/jacs.5b08744.
Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.
Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.
Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.
Klečka, M.; Slavětínská, L. Poštová; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides. Med. Chem. Commun. 2015, 6 (4), 576-580 DOI: 10.1039/C4MD00492B.
Klečka, M.; Slavětínská, L. Poštová; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides. Med. Chem. Commun. 2015, 6 (4), 576-580 DOI: 10.1039/C4MD00492B.
Tokarenko, A.; Slavětínská, L. Poštová; Klepetářová, B.; Hocek, M. Synthesis of Benzene and Pyridine 2-C-Methyl-C-ribonucleosides and -nucleotides. European Journal of Organic Chemistry 2015, 2015 (36), 7962-7983 DOI: 10.1002/ejoc.201501219.
Bednaříková, T.; Tošner, Z.; Horský, J.; Jindřich, J. Synthesis of C 3 -symmetric tri(alkylamino) guests and their interaction with cyclodextrins. Journal of Inclusion Phenomena and Macrocyclic Chemistry 2015, 81 (1-2), 141-152 DOI: 10.1007/s10847-014-0443-1.
2014
Kielkowski, P.; Fanfrlík, J.; Hocek, M. 7-Aryl-7-deazaadenine 2′-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations. Angewandte Chemie International Edition 2014, 53 (29), 7552-7555 DOI: 10.1002/anie.201404742.
Šnajdr, I.; Janoušek, Z.; Takagaki, M.; Císařová, I.; Hosmane, N. S.; Kotora, M. Alpha (α-) and beta (β-carboranyl-C-deoxyribosides: Syntheses, structures and biological evaluation. European Journal of Medicinal Chemistry 2014, 83, 389-397 DOI: 10.1016/j.ejmech.2014.06.005.
Dziuba, D.; Pohl, R.; Hocek, M. Bodipy-Labeled Nucleoside Triphosphates for Polymerase Synthesis of Fluorescent DNA. Bioconjugate Chemistry 2014, 25 (11), 1984-1995 DOI: 10.1021/bc5003554.
Hocek, M.; Ćerňová, M.; Pohl, R.; Klepetářová, B. C-H Trifluoromethylations of 1,3-Dimethyluracil and Reactivity of the Products in C-H Arylations. HETEROCYCLES 2014, 89 (5), 1159 DOI: 10.3987/COM-14-12958.
Krömer, M.; Klečka, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M. Chemoselective Synthesis of 4,5-Diarylpyrrolo[2,3-d]pyrimidines (6,7-Diaryl-7-deazapurines) by Consecutive Suzuki and Liebeskind-Srogl Cross-Couplings. European Journal of Organic Chemistry 2014, 2014 (32), 7203-7210 DOI: 10.1002/ejoc.201402882.
Popr, M.; Hybelbauerová, S.; Jindřich, J. A complete series of 6-deoxy-monosubstituted tetraalkylammonium derivatives of α-, β-, and γ-cyclodextrin with 1, 2, and 3 permanent positive charges. Beilstein Journal of Organic Chemistry 2014, 10, 1390-1396 DOI: 10.3762/bjoc.10.142.
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