Publications

Found 106 results
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2015
Ménová, P.; Dziuba, D.; Güixens-Gallardo, P.; Jurkiewicz, P.; Hof, M.; Hocek, M. Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction. Bioconjugate Chemistry 2015, 26 (2), 361-366 DOI: 10.1021/acs.bioconjchem.5b00006.
Dziuba, D.; Pohl, R.; Hocek, M. Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins. Chem. Commun. 2015, 51 (23), 4880-4882 DOI: 10.1039/C5CC00530B.
Popr, M.; Filippov, S. K.; Matushkin, N.; Dian, J.; Jindřich, J. Properties of cationic monosubstituted tetraalkylammonium cyclodextrin derivatives – their stability, complexation ability in solution or when deposited on solid anionic surface. Beilstein Journal of Organic Chemistry 2015, 11, 192-199 DOI: 10.3762/bjoc.11.20.
Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.
Klečka, M.; Slavětínská, L. Poštová; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides. Med. Chem. Commun. 2015, 6 (4), 576-580 DOI: 10.1039/C4MD00492B.
2014
Dziuba, D.; Pohl, R.; Hocek, M. Bodipy-Labeled Nucleoside Triphosphates for Polymerase Synthesis of Fluorescent DNA. Bioconjugate Chemistry 2014, 25 (11), 1984-1995 DOI: 10.1021/bc5003554.
Danhel, A.; Raindlová, V.; Havran, L.; Pivonkova, H.; Hocek, M.; Fojta, M. Electrochemical behaviour of 2,4-dinitrophenylhydrazi(o)ne as multi-redox centre DNA label at mercury meniscus modified silver solid amalgam electrode. Electrochimica Acta 2014, 126, 122-131 DOI: 10.1016/j.electacta.2013.09.147.
Jakl, M.; Straka, M.; Dytrtová, J. Jaklová; Roithová, J. Formation and stability of calcium complexes of dimethyl sulfoxide in water. International Journal of Mass Spectrometry 2014, 360, 8-14 DOI: 10.1016/j.ijms.2014.01.001.
Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; et al. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (20), 8268-8279 DOI: 10.1021/jm500497v.
Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; et al. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (20), 8268-8279 DOI: 10.1021/jm500497v.
Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; et al. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (20), 8268-8279 DOI: 10.1021/jm500497v.
Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; et al. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (20), 8268-8279 DOI: 10.1021/jm500497v.
Nauš, P.; Caletková, O.; Konečný, P.; Džubák, P.; Bogdanová, K.; Kolář, M.; Vrbková, J.; Slavětínská, L.; Tloušt’ová, E.; Perlíková, P.; et al. Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (3), 1097-1110 DOI: 10.1021/jm4018948.
Dhami, K.; Malyshev, D. A.; Ordoukhanian, P.; Kubelka, T.; Hocek, M.; Romesberg, F. E. Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet. Nucleic Acids Research 2014, 42 (16), 10235-10244 DOI: 10.1093/nar/gku715.
Danhel, A.; Raindlová, V.; Havran, L.; Barek, J.; Hocek, M.; Fojta, M. Voltammetric Study of dsDNA Modified by Multi-redox Label Based on N-methyl-4-hydrazino-7-nitrobenzofurazan. Electrochimica Acta 2014, 129, 348-357 DOI: 10.1016/j.electacta.2014.02.137.
2013
Perlíková, P.; Konečný, P.; Nauš, P.; Snášel, J.; Votruba, I.; Džubák, P.; Pichová, I.; Hajdúch, M.; Hocek, M. 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents. MedChemComm 2013, 4 (11), 1497 DOI: 10.1039/c3md00232b.
Dadová, J.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Aqueous Heck Cross-Coupling Preparation of Acrylate-Modified Nucleotides and Nucleoside Triphosphates for Polymerase Synthesis of Acrylate-Labeled DNA. The Journal of Organic Chemistry 2013, 78 (19), 9627-9637 DOI: 10.1021/jo4011574.
Veith, G. M.; Baggetto, L.; Adamczyk, L. A.; Guo, B.; Brown, S. S.; Sun, X. - G.; Albert, A. A.; Humble, J. R.; Barnes, C. E.; Bojdys, M. J.; et al. Electrochemical and Solid-State Lithiation of Graphitic C 3 N 4. Chemistry of Materials 2013, 25 (3), 503-508 DOI: 10.1021/cm303870x.
Veith, G. M.; Baggetto, L.; Adamczyk, L. A.; Guo, B.; Brown, S. S.; Sun, X. - G.; Albert, A. A.; Humble, J. R.; Barnes, C. E.; Bojdys, M. J.; et al. Electrochemical and Solid-State Lithiation of Graphitic C 3 N 4. Chemistry of Materials 2013, 25 (3), 503-508 DOI: 10.1021/cm303870x.
Kielkowski, P.; Brock, N. L.; Dickschat, J. S.; Hocek, M. Nucleobase Protection Strategy for Gene Cloning and Expression. ChemBioChem 2013, 14 (7), 801-804 DOI: 10.1002/cbic.201300127.
Sedlák, D.; Eignerová, B.; Dračínský, M.; Janoušek, Z.; Bartůněk, P.; Kotora, M. Synthesis and evaluation of 17α-(carboranylalkyl)estradiols as ligands for estrogen receptors α and β. Journal of Organometallic Chemistry 2013, 747, 178-183 DOI: 10.1016/j.jorganchem.2013.06.013.
Dadová, J.; Orság, P.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M. Vinylsulfonamide and Acrylamide Modification of DNA for Cross-linking with Proteins. Angewandte Chemie International Edition 2013, 52 (40), 10515-10518 DOI: 10.1002/anie.201303577.
2012
Ren, S.; Bojdys, M. J.; Dawson, R.; Laybourn, A.; Khimyak, Y. Z.; Adams, D. J.; Cooper, A. I. Porous, Fluorescent, Covalent Triazine-Based Frameworks Via Room-Temperature and Microwave-Assisted Synthesis. Advanced Materials 2012, 24 (17), 2357-2361 DOI: 10.1002/adma.201200751.
Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. Ann; Duchek, J.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Unexpected N -Demethylation of Oxymorphone and Oxycodone N -Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2706-2712 DOI: 10.1002/adsc.201200676.
2011
Číhalová, S.; Dziedzic, P.; Córdova, A.; Vesely, J. Asymmetric Aza-Morita-Baylis-Hillman-Type Reactions: The Highly Enantioselective Reaction between Unmodified α,β- Unsaturated Aldehydes and N-Acylimines by Organo-co-catalysis. Advanced Synthesis & Catalysis 2011, 353 (7), 1096-1108 DOI: 10.1002/adsc.201000951.
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