Publications

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Danhel, A.; Raindlová, V.; Havran, L.; Barek, J.; Hocek, M.; Fojta, M. Voltammetric Study of dsDNA Modified by Multi-redox Label Based on N-methyl-4-hydrazino-7-nitrobenzofurazan. Electrochimica Acta 2014, 129, 348-357 DOI: 10.1016/j.electacta.2014.02.137.
Danhel, A.; Trosanova, Z.; Balintová, J.; Havran, L.; Hocek, M.; Barek, J.; Fojta, M. Voltammetric analysis of 5-(4-Azidophenyl)-2′-deoxycytidine nucleoside and azidophenyl-labelled single- and double-stranded DNAs. Electrochimica Acta 2016, 215, 72-83 DOI: 10.1016/j.electacta.2016.08.096.
Dadová, J.; Orság, P.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M. Vinylsulfonamide and Acrylamide Modification of DNA for Cross-linking with Proteins. Angewandte Chemie International Edition 2013, 52 (40), 10515-10518 DOI: 10.1002/anie.201303577.
Fojta, M.; Havran, L.; Havranova-Vidlakova, P.; Hocek, M.; Krömer, M.; Sykorova, V.; Trefulka, M. Vicinal Diol-Tethered Nucleobases as Targets for DNA Redox Labeling with Osmate Complexes. Chembiochem : a European journal of chemical biology 2020, 21 (1-2), 171-180 DOI: 10.1002/cbic.201900388.
Havranova-Vidlakova, P.; Kroemer, M.; Sykorova, V.; Trefulka, M.; Fojta, M.; Havran, L.; Hocek, M. Vicinal Diol-Tethered Nucleobases as Targets for DNA Redox Labeling with Osmate Complexes. Chembiochem 2019 DOI: 10.1002/cbic.201900388.
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Gallardo, P. Güixens; Hocek, M.; Hof, M.; Humpolickova, J.; Jurkiewicz, P.; Kraus, T.; Miclea, S. Paul; Pohl, R. Thiophene-linked tetramethylbodipy-labeled nucleotide for viscosity-sensitive oligonucleotide probes of hybridization and protein-DNA interactions. Organic and Biomolecular Chemistry 2020, 18 (5), 912-919 DOI: 10.1039/c9ob02634g.
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Džubák, P.; Gurska, S.; Hajdúch, M.; Hocek, M.; Pavliš, P.; Pohl, R.; Tichý, M.; Yang, C. Synthesis, Photophysical Properties, and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides. Journal of Organic Chemistry 2020, 85 (12), 8085-8101 DOI: 10.1021/acs.joc.0c00927.
Kubelka, T.; Slavětínská, L.; Hocek, M. Synthesis of Substituted Benzyl Homo-C-Ribonucleosides and -Nucleotides as Carba Analogues of Phosphoribosylanthranilate. European Journal of Organic Chemistry 2012, 2012 (26), 4969-4981 DOI: 10.1002/ejoc.201200819.
A. Downey, M.; Pohl, R.; Roithová, J.; Hocek, M. Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism. Chemistry-a European Journal 2017, 23 (16), 3910-3917 DOI: 10.1002/chem.201604955.
Kalachova, L.; Pohl, R.; Bednárová, L.; Fanfrlík, J.; Hocek, M. Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations. Org. Biomol. Chem. 2013, 11 (1), 78-89 DOI: 10.1039/C2OB26881G.
Raindlová, V.; Pohl, R.; Klepetářová, B.; Havran, L.; Šimková, E.; Horáková, P.; Pivonkova, H.; Fojta, M.; Hocek, M. Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling. ChemPlusChem 2012, 77 (8), 652-662 DOI: 10.1002/cplu.201200056.
Sabat, N.; Nauš, P.; Matyašovský, J.; Dziuba, D.; Slavětínská, L.; Hocek, M. Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions. Synthesis 2016, 48 (07), 1029-1045 DOI: 10.1055/s-0035-1561287.
Krömer, M.; Bartova, K.; Raindlová, V.; Hocek, M. Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations. Chemistry-a European Journal 2018, 24 (46), 11890-11894 DOI: 10.1002/chem.201802282.
Malnuit, V.; Smolen, S.; Tichý, M.; Slavětínská, L. Poštová; Hocek, M. Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6-(Thiophen-2-yl)-7-fluoro-7-deazapurine. European Journal of Organic Chemistry 2019, 2019 (31-32), 5409-5423 DOI: 10.1002/ejoc.201900509.
Novák, P.; Pohl, R.; Kotora, M.; Hocek, M. Synthesis of C-Aryldeoxyribosides by [2 + 2 + 2]-Cyclotrimerization Catalyzed by Rh, Ni, Co, and Ru Complexes. Organic Letters 2006, 8 (10), 2051-2054 DOI: 10.1021/ol060454m.
Tokarenko, A.; Slavětínská, L. Poštová; Klepetářová, B.; Hocek, M. Synthesis of Benzene and Pyridine 2-C-Methyl-C-ribonucleosides and -nucleotides. European Journal of Organic Chemistry 2015, 2015 (36), 7962-7983 DOI: 10.1002/ejoc.201501219.
Hocek, M. Synthesis of Base-Modified 2′-Deoxyribonucleoside Triphosphates and Their Use in Enzymatic Synthesis of Modified DNA for Applications in Bioanalysis and Chemical Biology. The Journal of Organic Chemistry 2014, 79 (21), 9914-9921 DOI: 10.1021/jo5020799.
Raindlová, V.; Pohl, R.; Hocek, M. Synthesis of Aldehyde-Linked Nucleotides and DNA and Their Bioconjugations with Lysine and Peptides through Reductive Amination. Chemistry - A European Journal 2012, 18 (13), 4080-4087 DOI: 10.1002/chem.201103270.
Chapuis, H.; Kubelka, T.; Joubert, N.; Pohl, R.; Hocek, M. Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2′-Deoxyribonucleosides. European Journal of Organic Chemistry 2012, 2012 (9), 1759-1767 DOI: 10.1002/ejoc.201101662.
Perlíková, P.; Martínez, N. Jornet; Slavětínská, L.; Hocek, M. Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines. Tetrahedron 2012, 68 (39), 8300-8310 DOI: 10.1016/j.tet.2012.07.033.
Kubelka, T.; Slavětínská, L.; Eigner, V.; Hocek, M. Synthesis of 2,6-disubstituted pyridin-3-yl C-2′-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides. Organic & Biomolecular Chemistry 2013, 11 (28), 4702 DOI: 10.1039/c3ob40774h.
Nauš, P.; Caletková, O.; Konečný, P.; Džubák, P.; Bogdanová, K.; Kolář, M.; Vrbková, J.; Slavětínská, L.; Tloušt’ová, E.; Perlíková, P.; et al. Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (3), 1097-1110 DOI: 10.1021/jm4018948.
Perlíková, P.; Eberlin, L.; Ménová, P.; Raindlová, V.; Slavětínská, L.; Tloušťová, E.; Bahador, G.; Lee, Y. - J.; Hocek, M. Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines. ChemMedChem 2013, 8 (5), 832-846 DOI: 10.1002/cmdc.201300047.
Klečka, M.; Slavětínská, L. Poštová; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides. Med. Chem. Commun. 2015, 6 (4), 576-580 DOI: 10.1039/C4MD00492B.
Bartova, K.; Džubák, P.; Fleuti, M. Heidi; Gurska, S.; Hajdúch, M.; Hocek, M.; Pavliš, P.; Slavětínská, L. Poštová; Tichý, M.; Tloušťová, E. Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides. Journal of Organic Chemistry 2020, 85 (16), 10539-10551 DOI: 10.1021/acs.joc.0c00928.
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